Results 101 to 110 of about 54,023 (335)

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Block two-stage preconditioners

Applied Mathematics Letters, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Castel, M.J, Migallón, V, Penadés, J
openaire   +1 more source

The analysis of FETI-DP preconditioner for full DG discretization of elliptic problems [PDF]

, 2014
Maksymilian Dryja, Juan Galvis, Marcus Sarkis   +2 more
openalex   +1 more source

Inherently Disordered Auxetic Metamaterials

Advanced Science, EarlyView.
Inherently disordered auxetic metamaterials based on random chiral Delaunay triangulations are designed and investigated using numerical simulations and experimental tests. These disordered frameworks exhibit orthotropic behavior and a large negative Poisson's ratio (ca.
Matteo Montanari, Reza Moghimimonfared, Andrea Spaggiari, Luke Mizzi   +3 more
wiley   +1 more source

Improved sweeping preconditioners for domain decomposition algorithms applied to time-harmonic Helmholtz and Maxwell problems★★★

ESAIM: Proceedings and Surveys, 2018
Sweeping-type algorithms have recently gained a lot of interest for the solution of highfrequency time-harmonic wave problems, in particular when used in combination with perfectly matched layers.
Vion Alexandre, Geuzaine Christophe
doaj   +1 more source

Limb Ischemic Preconditioning for Open Heart Surgery in Infants [PDF]

, 2011
B. Oc, Ateş Duman, Wenwu Zhou
openalex   +1 more source

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source

α-linolenic omega-3 fatty acid for stroke protection: from brain preconditioning paradigm to nutrition

Oléagineux, Corps gras, Lipides, 2011
Stroke is the third leading cause of death, due to its high incidence, the severity of the insult, and lack of treatment options. The only therapeutic is restoration of cerebral blood flow achieved by recombinant tissue plasminogen activator treatment ...
Blondeau Nicolas
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Modified Preconditioned GAOR Methods for Systems of Linear Equations

Journal of Applied Mathematics, 2013
Three kinds of preconditioners are proposed to accelerate the generalized AOR (GAOR) method for the linear system from the generalized least squares problem. The convergence and comparison results are obtained.
Xue-Feng Zhang, Qun-Fa Cui, Shi-Liang Wu
doaj   +1 more source