Results 111 to 120 of about 52,672 (321)

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice [PDF]

, 2020
Chandra Mohan Tamatam, Narsa M. Reddy, Haranatha R. Potteti, Aparna Ankireddy, Patrick Noone, Masayuki Yamamoto, Thomas W. Kensler, Sekhar P. Reddy   +7 more
openalex   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Modified Preconditioned GAOR Methods for Systems of Linear Equations

Journal of Applied Mathematics, 2013
Three kinds of preconditioners are proposed to accelerate the generalized AOR (GAOR) method for the linear system from the generalized least squares problem. The convergence and comparison results are obtained.
Xue-Feng Zhang, Qun-Fa Cui, Shi-Liang Wu
doaj   +1 more source

Quantum computing and preconditioners for hydrological linear systems. [PDF]

Sci Rep, 2022
Golden J, O'Malley D, Viswanathan H.
europepmc   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

α-linolenic omega-3 fatty acid for stroke protection: from brain preconditioning paradigm to nutrition

Oléagineux, Corps gras, Lipides, 2011
Stroke is the third leading cause of death, due to its high incidence, the severity of the insult, and lack of treatment options. The only therapeutic is restoration of cerebral blood flow achieved by recombinant tissue plasminogen activator treatment ...
Blondeau Nicolas
doaj   +1 more source

Reconstructing Kernel-Based Machine Learning Force Fields with Superlinear Convergence. [PDF]

J Chem Theory Comput, 2023
Blücher S, Müller KR, Chmiela S.
europepmc   +1 more source

Finite-difference preconditioners for superconsistent pseudospectral approximations [PDF]

, 2007
Lorella Fatone, Daniele Funaro, Valentina Scannavini   +2 more
openalex   +1 more source

Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway

, 2022
Chengyu Mao, Tiantian Zhang, Dongjiu Li, En Zhou, Yuqi Fan, Qing He, Changqian Wang, Junfeng Zhang   +7 more
openalex   +1 more source