Precursor NK cell lymphoblastic leukemia/lymphoma - report of a case with literature review [PDF]
Precursor Natural Killer cell lymphoblastic leukemia/lymphoma is a rare entity defined clearly by WHO (2008 WHO classification). However, the pathobiology of this subset of neoplasms is not clearly defined.
Sonal Jain +3 more
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Acute lymphoblastic leukemia is predominantly found in children. It is a neoplasm of precursor cells or lymphoblasts committed to either a B- or T-cell lineage.
Alicia C. Hirzel +3 more
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Precursor T-Cell acute lymphoblastic leukemia/lymphoma with rare presentation in the urinary bladder [PDF]
We present the 16th reported case of Acute Lymphoblastic Leukemia (ALL) with involvement in the bladder. Our patient was a 22 yearold man with T-cell ALL with a mediastinal mass.
Alexander Pham +5 more
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A Bibliometric Analysis of Drug Resistance in Pediatric Acute Lymphoblastic Leukemia [PDF]
Background: Despite the improved outcomes in acute lymphoblastic leukemia (ALL), drug resistance remains a major challenge. This study provides the first overview of global research trends in pediatric ALL drug resistance, highlighting emerging ...
Alireza Khanahmad +3 more
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Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) is a high-risk and biologically distinct subset of T-cell acute lymphoblastic leukemia, typically characterized by leukemic involvement of bone marrow, peripheral blood, and ...
Violet O. Swart, Behyar Zoghi
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Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma [PDF]
AbstractPatients with relapsed/refractory early T-cell precursor lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) respond poorly to traditional therapy and have dismal prognosis. CD7 is a promising therapeutic targets for chimeric antigen receptor modified T cell therapy (CART) due to its widely expression in almost all T-cell malignancies.
Hai-ping Dai +9 more
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CBFA2T3::GLIS2‐positive acute leukemia with RAM and mixed T/megakaryocytic phenotype
Herein, we present a rare case of acute myeloid leukemia (AML) with CBFA2T3‐rearrangement and the expression of megakaryocytic and lymphoid markers, highlighting the need for a high suspicion index in differential diagnosis and applying adequate workup ...
Mahsa Khanlari +8 more
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Development‐dependent expression of cyclin D3 in precursor T‐cell lymphoblastic leukemia/lymphoma [PDF]
In contrast to the clear oncogenic role of cyclins D1 and D2, cyclin D3 is suggested to have a role in the initiation and/or maintenance of differentiation in a lineage‐associated manner in addition to its basic role in proliferation. Recently, it has been reported that in cyclin D3‐deficient mice, normal expansion of T lymphocytes is impaired because ...
Eiichi, Sasaki +7 more
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An unusual presentation of precursor T cell lymphoblastic leukemia/lymphoma with cholestatic jaundice: case report [PDF]
Cholestatic jaundice as a presenting symptom of Precursor T-lymphoblastic leukemia (T-ALL)/lymphoma (T-LBL) has never been reported in literature. Similarly, precursor T-ALL/T-LBL is characteristically negative for synaptophysin. We report the first case of a patient with precursor T-ALL/T-LBL who presented with cholestatic jaundice and aberrant tumor ...
Latif Sahibzada U +2 more
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Transformation of acute lymphoblastic leukemia with a precursor B-cell immunophenotype to burkitt’s lymphoma: A case report [PDF]
Background: As a new point, some very rare features can be revealed as initial diagnosis of acute lymphoblastic leukemia (ALL) without any evidence of lymphoma-like behavior which after initial recovery, presents with new evidence of lymphoma.
Masoumeh Jafari +2 more
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