Results 11 to 20 of about 5,396,547 (212)

Flow Cytometry-Guided Diagnosis of Cortical T-Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement. [PDF]

J Clin Lab Anal
ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Glait-Santar C, Moshe Y, Ayelet IA, Katz BZ.   +3 more
europepmc   +2 more sources

Bortezomib-based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single-center retrospective study. [PDF]

Pediatr Investig
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Zhao X, Wang J, Que L, Zhou D, Fang J, Xu L.   +5 more
europepmc   +2 more sources

Allogeneic Hematopoietic Stem Cell Transplantation Achieves Durable Remission in Blast-Phase Chronic Myeloid Leukemia Presenting as Early T-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]

EJHaem
ABSTRACT Introduction The presentation of chronic myeloid leukemia (CML) in the blast phase as early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) is very rare. As previously reported, in contrast to B‐ALL, the prognosis is poor. Case Presentation We encountered a patient with blast phase CML presenting as ETP‐ALL.
Tsushima T, Konishi Y, Yoda N, Wada K, Okamoto K, Matsuo K, Isogai S, Shimoji S, Utsu Y, Masuda SI, Aotsuka N.   +10 more
europepmc   +2 more sources

Expressió de ZAP-70 en linfòcits B normals i síndromes limfoproliferatives B [PDF]

, 2006
[cat] La Leucèmia Limfàtica Crònica (LLC), la més freqüent de les leucèmies en el món occidental, és una malaltia produïda per la proliferació i cúmul de limfòcits B madurs, actualment incurable.
Crespo Maull, Marta
core   +6 more sources

CD19-NEGATIVE B-LYMPHOBLASTIC LEUKEMIA/LYMPHOMA: A CASE REPORT

Hematology, Transfusion and Cell Therapy, 2021
Lymphoblasts in B-lymphoblastic leukemia/lymphoma are almost always positive for the B-cell markers CD19, cytCD79a and cytCD22 and, according to the revised 4th edition of the World Health Organization (WHO) classification of tumours of haematopoietic ...
NA Marcondes, BM Spindler, Ld Olivo, MS Vieira, FB Fernandes   +4 more
doaj   +1 more source

Gene expression profiling of precursor T-cell lymphoblastic leukemia/lymphoma identifies oncogenic pathways that are potential therapeutic targets [PDF]

Leukemia, 2007
We compared the gene expression pattern of thymic tumors from precursor T-cell lymphoblastic lymphoma/leukemia (pre-T LBL) that arose in transgenic mice that overexpressed SCL, LMO1 or NUP98-HOXD13 (NHD13) with that of thymocytes from normal littermates.
Y-W, Lin, P D, Aplan
openaire   +2 more sources

FLT3 mutations in Early T-Cell Precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors [PDF]

, 2013
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-risk subgroup of acute T-lymphoblastic leukemia (T-ALL) with a high rate of FLT3-mutations in adults.
Hartmut Döhner (276603), Hofmann, Wolf-Karsten, Christian Brandts, Ulrich Dührsen, Eckhard Thiel (66496), Mochmann, Liliana H., Burmeister, Thomas, Lars Fransecky, Neumann, Martin, Döhner, Hartmut, Eckhard Thiel, Nicola Gökbuget, Claudia D Baldus, Martin Griesshammer (276602), Rainer Haas (81562), Sartangi, Nasrin Farhadi, Martin Neumann (276593), Gerhard Ehninger, Schwartz, Stefan, Dieter Hoelzer, Stefan Schwartz (276600), Nicola Gökbuget (276599), Olga Blau, Isabelle Bartram, Bartram, Isabelle, Thiel, Eckhard, Liliana H Mochmann, Wolf-Karsten Hofmann, Thomas Burmeister, Martin Neumann, Martin Griesshammer, Sandra Heesch (276598), Heesch, Sandra, Haas, Rainer, Rainer Haas, Schlee, Cornelia, Fransecky, Lars, Ulrich Dührsen (106782), Griesshammer, Martin, Christian Brandts (276601), Lars Fransecky (276595), Ebru Coskun, Claudia D. Baldus (66494), Isabelle Bartram (276596), Wolf-Karsten Hofmann (66497), Ehninger, Gerhard, Brandts, Christian Hubertus, Baldus, Claudia, Gerhard Ehninger (106788), Dührsen, Ulrich, Hoelzer, Dieter, Cornelia Schlee, Dieter Hoelzer (551), Cornelia Schlee (105296), Ebru Coskun (276594), Gökbuget, Nicola, Sandra Heesch, Liliana H. Mochmann (105294), Hartmut Döhner, Nasrin Farhadi Sartangi, Nasrin Farhadi Sartangi (276597), Thomas Burmeister (276604), Stefan Schwartz, Coskun, Ebru, Olga Blau (276605), Blau, Olga   +65 more
core   +2 more sources

Clinical and molecular characterization of early T-cell precursor leukemia : a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations [PDF]

, 2012
A subgroup of pediatric acute T-lymphoblastic leukemia (T-ALL) was characterized by a gene expression profile comparable to that of early T-cell precursors (ETPs) with a highly unfavorable outcome.
Hoelzer, Dieter, Farhadi-Sartangi, Nasrin, Schlee, Cornelia, Hofmann, Wolf-Karsten, Thiel, Eckhard, Burmeister, Thomas, Neumann, Martin, Thibaut, Julia, Gökbuget, Nicola, Heesch, Sandra, Schwartz, Stefan, Benlasfer, Ouidad, Baldus, Claudia   +12 more
core   +1 more source

Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype [PDF]

Blood, 2016
Key Points Adult patients with ETP-ALL/LBL have poor long-term outcomes. Novel therapies are urgently needed for adult patients with ETP-ALL/LBL.
Nitin, Jain, Audrey V, Lamb, Susan, O'Brien, Farhad, Ravandi, Marina, Konopleva, Elias, Jabbour, Zhuang, Zuo, Jeffrey, Jorgensen, Pei, Lin, Sherry, Pierce, Deborah, Thomas, Michael, Rytting, Gautam, Borthakur, Tapan, Kadia, Jorge, Cortes, Hagop M, Kantarjian, Joseph D, Khoury   +16 more
openaire   +2 more sources

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]

, 2012
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo, Groiss, Volker, Schneider, Katja, Renier J Brentjens, Nadia Terziyska, Harald Ehrhardt, Jeremias, I., Brentjens, Renier J., Farkasova, K., Katja Schneider, Volker Groiss (106787), Katarina Farkasova (106794), Ehrhardt, Harald, Wagner, E., Renier J. Brentjens (106801), Quintanilla-Martinez, Leticia, Martin Horstmann (45040), Ehrhardt, H., Ernst Wagner (60760), Wagner, Ernst, Leticia Quintanilla-Martinez (33277), Terziyska, N., Katja Schneider (106791), Horstmann, M., Brentjens, R.J., Catarina Castro Alves, Quintanilla-Martinez, L., Zur Stadt, U., Horstmann, Martin, Schneider, K., Ogris, M., Manfred Ogris, Alves, C.C., Nadia Terziyska (106777), Terziyska, Nadia, Jeremias, Irmela, Groiss, V., Irmela Jeremias (106806), Volker Groiss, Udo zur Stadt, Martin Horstmann, Farkasova, Katarina, Ernst Wagner, Irmela Jeremias, Ogris, Manfred, Udo zur Stadt (106803), Catarina Castro Alves (106783), Manfred Ogris (60759), Castro Alves, Catarina, Katarina Farkasova, Leticia Quintanilla-Martinez, Harald Ehrhardt (106798)   +51 more
core   +2 more sources