Synchronous childhood T-lymphoblastic lymphoma and B-cell precursor acute lymphoblastic leukemia associated with constitutional MMR deficiency syndrome –a case report [PDF]
We present a four-year-old girl with synchronous T-cell lymphoblastic lymphoma (T-LBL) and B-cell precursor acute lymphoblastic leukemia (BCP-ALL).Development of two lymphoid malignancies arising from completely different cell lineages was confirmed by ...
Joanna Bulsa +5 more
doaj +2 more sources
Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma
Precursor B-cell lymphoblastic lymphoma (LBL) occurring as a primary bone tumor is a rare clinical presentation in children, and data regarding this condition are limited to small case series or a few individual case reports.
Shwetha Seetharam +3 more
doaj +2 more sources
Transformation of acute lymphoblastic leukemia with a precursor B-cell immunophenotype to burkitt’s lymphoma: A case report [PDF]
Background: As a new point, some very rare features can be revealed as initial diagnosis of acute lymphoblastic leukemia (ALL) without any evidence of lymphoma-like behavior which after initial recovery, presents with new evidence of lymphoma.
Masoumeh Jafari +2 more
doaj
Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B-cell Precursor Acute Lymphoblastic Leukemia [PDF]
Patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) have a favorable prognosis. However, current treatment protocols are based on intensive cytotoxic chemotherapy and therapy options are limited when patients relapse. Hence, there is an
Gina Münch +46 more
core +1 more source
CD19-NEGATIVE B-LYMPHOBLASTIC LEUKEMIA/LYMPHOMA: A CASE REPORT
Lymphoblasts in B-lymphoblastic leukemia/lymphoma are almost always positive for the B-cell markers CD19, cytCD79a and cytCD22 and, according to the revised 4th edition of the World Health Organization (WHO) classification of tumours of haematopoietic ...
NA Marcondes +4 more
doaj +1 more source
Gene expression profiling of precursor T-cell lymphoblastic leukemia/lymphoma identifies oncogenic pathways that are potential therapeutic targets [PDF]
We compared the gene expression pattern of thymic tumors from precursor T-cell lymphoblastic lymphoma/leukemia (pre-T LBL) that arose in transgenic mice that overexpressed SCL, LMO1 or NUP98-HOXD13 (NHD13) with that of thymocytes from normal littermates.
Y-W, Lin, P D, Aplan
openaire +2 more sources
Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype [PDF]
Key Points Adult patients with ETP-ALL/LBL have poor long-term outcomes. Novel therapies are urgently needed for adult patients with ETP-ALL/LBL.
Nitin, Jain +16 more
openaire +2 more sources
Toll-like Receptors 2, 3, and 4 in Childhood Acute Lymphocytic Leukemia
Introduction: Acute lymphocytic leukemia (ALL) is the most common cancer type in children and accounts for 80% of pediatric leukemias. Novel targets are necessary to improve survival rates for refractory and relapsed disease.
Matheus Loureiro da Silva Cruz +11 more
doaj +1 more source
OBJECTIVE: To determine the diagnostic importance of immunohistochemistry (IHC) in classifying acute lymphoblastic leukemia (ALL) in a tertiary care center.
Nazish Farooq +3 more
doaj +1 more source
B-cell precursor acute lymphoblastic leukemia (BCP-ALL), which is the most common type of ALL, has an excellent prognosis with long-term event-free survival of 90%.
Jianne Lee, Sun Young Kim, Yeon Jung Lim
doaj +1 more source

