Results 21 to 30 of about 50,246 (189)

Development‐dependent expression of cyclin D3 in precursor T‐cell lymphoblastic leukemia/lymphoma [PDF]

Pathology International, 2007
In contrast to the clear oncogenic role of cyclins D1 and D2, cyclin D3 is suggested to have a role in the initiation and/or maintenance of differentiation in a lineage‐associated manner in addition to its basic role in proliferation. Recently, it has been reported that in cyclin D3‐deficient mice, normal expansion of T lymphocytes is impaired because ...
Eiichi, Sasaki, Yasushi, Yatabe, Mitsuyoshi, Hashimoto, Yoriko, Yamashita, Yuichi, Hasegawa, Hiroshi, Kojima, Toshiro, Nagasawa, Naoyoshi, Mori   +7 more
openaire   +3 more sources

Outcome of Patients with T-Cell Acute Lymphoblastic Leukemia/Lymphoma with Early T-Cell Precursor-like Immunophenotype with Strong CD5 Expression

Blood, 2020
Introduction: T-cell acute lymphoblastic leukemia (T-ALL) originating from early T-cell precursors (ETP-ALL) has distinct immunophenotype (CD1a-CD8-CD5-/weak and positive for myeloid or stem-cell markers [My-HSC+]) and is associated with poor outcome with 5-year (yr) survival <25%. Some T-ALL cases are transcriptionally similar to
Kiyomi Morita, Hagop M. Kantarjian, Hong Fang, Farhad Ravandi, Nitin Jain, Marina Konopleva, El Hussein Siba, Feng Wang, Nicholas J. Short, Koichi Takahashi, Rita Khouri, Koji Sasaki, Courtney D. DiNardo, Tapan M. Kadia, Guillermo Garcia-Manero, Naval Daver, Guillermo Montalban Bravo, Sergej Konoplev, Joseph D. Khoury, Elias Jabbour   +19 more
openaire   +2 more sources

Isolated Central Nervous System Presentation of Early T-Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma: A Rare Case of Exclusive Brain Involvement

Case Reports in Hematology
Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) is a high-risk and biologically distinct subset of T-cell acute lymphoblastic leukemia, typically characterized by leukemic involvement of bone marrow, peripheral blood, and ...
Violet O. Swart, Behyar Zoghi
doaj   +3 more sources

Emerging Necessity of Myeloid Mutational Analysis in Early T-cell Precursor Acute Lymphoblastic Leukemia/Lymphoma (ETP-ALL)

Turkish Journal of Hematology, 2023
Early T-cell precursor (ETP) acute lymphoblastic leukemia/ lymphoma (ETP-ALL) is a unique subtype of T-lymphoblastic leukemia (T-ALL) characterized by its distinct immunophenotypic profile and genetic signature. First described in 2009 as a type of T-ALL
Hamza Tariq, Sindhu Shetty
openaire   +4 more sources

PB1754: HOMOZYGOUS DELETION OF ETV6: EARLY T-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA OR PRECURSOR T-LYMPHOBLASTIC LYMPHOMA

HemaSphere, 2023
Precursor T-lymphoblastic lymphoma (T-LBL), which is biologically similar to precursor T-acute lymphoblastic leukemia (T-ALL), is derived from immature lymphoid cells of T-cell lineage.
Miguel Ángel Perera Álvarez, Juan Francisco Rodríguez López, Jorge Rodríguez-Afonso, Paula Reyes-González-Casanova, Dolly Viviana Fiallo Suarez, Maria Angelina Lemes Castellano, Maria Violeta Vidal Ballester, Ruth Stuckey, Carlos Rodriguez Medina, Cristina Bilbao, Maria Teresa Gomez Casares   +10 more
doaj   +2 more sources

Signal Pathway in Precursor B-Cell Lymphoblastic Leukemia/Lymphoma

, 2017
Stat5, c-myc, Hipk2, Fiz1, and ZFP521 to lymphomagenesis precursor B-cell lymphoblastic lymphoma/leukemia have been previously identified as a putative gene involved in the induction of B-cell lymphomagenesis.
Tatsuaki Tsuruyama, Takuya Hiratsuka
openaire   +3 more sources

CBFA2T3::GLIS2‐positive acute leukemia with RAM and mixed T/megakaryocytic phenotype

eJHaem, 2023
Herein, we present a rare case of acute myeloid leukemia (AML) with CBFA2T3‐rearrangement and the expression of megakaryocytic and lymphoid markers, highlighting the need for a high suspicion index in differential diagnosis and applying adequate workup ...
Mahsa Khanlari, Lu Wang, Christine Y Bolen, Felipe Sebastian Bautista Otanez, Larissa V. Furtado, Laura Key, Lisa Irwin, Wei Wang, Jeffery M. Klco   +8 more
doaj   +1 more source

Correspondance: Venetoclax combined with FLAG-based chemotherapy induces rapid and deep responses in early T-cell precursor lymphoblastic leukemia/lymphoma. Report of two cases and review of the literature. [PDF]

Ann Hematol
Dereme J, Segot A, Nabergoj M, Dewarrat N, Basset V, Blum S, Tsilimidos G.   +6 more
europepmc   +2 more sources

Transformation of acute lymphoblastic leukemia with a precursor B-cell immunophenotype to burkitt’s lymphoma: A case report [PDF]

Caspian Journal of Internal Medicine, 2023
Background: As a new point, some very rare features can be revealed as initial diagnosis of acute lymphoblastic leukemia (ALL) without any evidence of lymphoma-like behavior which after initial recovery, presents with new evidence of lymphoma.
Masoumeh Jafari, Shahla Ansari Damavandi, Forugh Charmduzi   +2 more
doaj  

CD19-NEGATIVE B-LYMPHOBLASTIC LEUKEMIA/LYMPHOMA: A CASE REPORT

Hematology, Transfusion and Cell Therapy, 2021
Lymphoblasts in B-lymphoblastic leukemia/lymphoma are almost always positive for the B-cell markers CD19, cytCD79a and cytCD22 and, according to the revised 4th edition of the World Health Organization (WHO) classification of tumours of haematopoietic ...
NA Marcondes, BM Spindler, Ld Olivo, MS Vieira, FB Fernandes   +4 more
doaj   +1 more source