Results 11 to 20 of about 59,825 (253)

Human medicines European public assessment report (EPAR): Spectrila, asparaginase, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Date of authorisation: 14/01/2016, Revision: 3, Status: Authorised [PDF]

Case Medical Research, 2019
Kernel Networks Inc.
semanticscholar   +3 more sources

Emerging Necessity of Myeloid Mutational Analysis in Early T-cell Precursor Acute Lymphoblastic Leukemia/Lymphoma (ETP-ALL)

Turkish Journal of Hematology, 2023
Early T-cell precursor (ETP) acute lymphoblastic leukemia/ lymphoma (ETP-ALL) is a unique subtype of T-lymphoblastic leukemia (T-ALL) characterized by its distinct immunophenotypic profile and genetic signature. First described in 2009 as a type of T-ALL
Hamza Tariq, Sindhu Shetty
semanticscholar   +5 more sources

PB1754: HOMOZYGOUS DELETION OF ETV6: EARLY T-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA OR PRECURSOR T-LYMPHOBLASTIC LYMPHOMA

HemaSphere, 2023
Precursor T-lymphoblastic lymphoma (T-LBL), which is biologically similar to precursor T-acute lymphoblastic leukemia (T-ALL), is derived from immature lymphoid cells of T-cell lineage.
Miguel Ángel Perera Álvarez, Juan Francisco Rodríguez López, Jorge Rodríguez-Afonso, Paula Reyes-González-Casanova, Dolly Viviana Fiallo Suarez, Maria Angelina Lemes Castellano, Maria Violeta Vidal Ballester, Ruth Stuckey, Carlos Rodriguez Medina, Cristina Bilbao, Maria Teresa Gomez Casares   +10 more
doaj   +3 more sources

Human medicines European public assessment report (EPAR): Blincyto, blinatumomab, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Date of authorisation: 23/11/2015, Revision: 9, Status: Authorised [PDF]

Case Medical Research, 2019
Kernel Networks Inc.
semanticscholar   +4 more sources

Haplo-Identical Non-Gene Editing CD7 CAR T-Cells Induced Bone Marrow and Extramedullary Remission in a Pediatric Patient with TP53 Mutated Relapsed and Refractory Early T-Cell Precursor Lymphoblastic Leukemia/Lymphoma after Haploidentical Hematopoietic Stem Cell Transplantation

Blood, 2021
Abstract Patients with relapsed/refractory early T-cell precursor lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) respond poorly to traditional therapy and have dismal prognosis. CD7 expresses in almost all blasts of T-cell lymphoma/leukemia and represents one of the most promising therapeutic targets for T-ALL/LBL by CD7 targeted chimeric
Haiping Dai, Yang Lin, Huimin Meng, Qingya Cui, Wenjuan Zhu, Xiaowen Tang, Wei Cui, Depei Wu   +7 more
semanticscholar   +3 more sources

Signal Pathway in Precursor B-Cell Lymphoblastic Leukemia/Lymphoma

, 2017
Tatsuaki Tsuruyama, Takuya Hiratsuka
semanticscholar   +5 more sources

Multi-Institution Review of Adult Early T-Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma (ETP-ALL)

Blood, 2015
Abstract Background: The Early T-cell precursor (ETP) variant of acute lymphoblastic lymphoma/leukemia (ALL) is a recognized high risk variant, recognized by the absence of CD1a, with aberrant myeloid antigen expression (CD13, CD33, CD117, and CD34), and frequent absence of CD4 or CD8. Treatment intensification may improve
Bijal Shah, Uma Borate, Vamsi Kota, Ling Zhang, Deniz Peker, Amanda Redden Hathaway, Julio C. Chávez   +6 more
semanticscholar   +3 more sources

A Comparative Analysis of Early T-Cell Precursor Lymphoblastic Leukemia/Lymphoma (ETP-ALL/LBL) and Non-ETP-ALL/LBL in a Tertiary Cancer Care Center Based in Western India [PDF]

Indian Journal of Hematology and Blood Transfusion, 2023
Early T-cell precursor lymphoblastic leukemia (ETP-ALL) has a unique immunophenotype with very early T-cell differentiation. The current study summarises the distinct clinicopathological aspects of ETP-ALL and compares them with non-ETP-ALL. Twenty-nine ETP-ALL and 191 non-ETP-ALL cases were retrieved between 2018 and 2021. A P value was determined for
Anurag Saha, Beena Brahmbhatt, Varnika Rai, Sneha Kakoty, Jyoti Sawhney   +4 more
openalex   +3 more sources

Development‐dependent expression of cyclin D3 in precursor T‐cell lymphoblastic leukemia/lymphoma [PDF]

Pathology International, 2007
In contrast to the clear oncogenic role of cyclins D1 and D2, cyclin D3 is suggested to have a role in the initiation and/or maintenance of differentiation in a lineage‐associated manner in addition to its basic role in proliferation. Recently, it has been reported that in cyclin D3‐deficient mice, normal expansion of T lymphocytes is impaired because ...
Eiichi, Sasaki, Yasushi, Yatabe, Mitsuyoshi, Hashimoto, Yoriko, Yamashita, Yuichi, Hasegawa, Hiroshi, Kojima, Toshiro, Nagasawa, Naoyoshi, Mori   +7 more
openaire   +3 more sources

Outcome of Patients with T-Cell Acute Lymphoblastic Leukemia/Lymphoma with Early T-Cell Precursor-like Immunophenotype with Strong CD5 Expression

Blood, 2020
Introduction: T-cell acute lymphoblastic leukemia (T-ALL) originating from early T-cell precursors (ETP-ALL) has distinct immunophenotype (CD1a-CD8-CD5-/weak and positive for myeloid or stem-cell markers [My-HSC+]) and is associated with poor outcome with 5-year (yr) survival <25%. Some T-ALL cases are transcriptionally similar to
Kiyomi Morita, Hagop M. Kantarjian, Hong Fang, Farhad Ravandi, Nitin Jain, Marina Konopleva, El Hussein Siba, Feng Wang, Nicholas J. Short, Koichi Takahashi, Rita Khouri, Koji Sasaki, Courtney D. DiNardo, Tapan M. Kadia, Guillermo Garcia-Manero, Naval Daver, Guillermo Montalban Bravo, Sergej Konoplev, Joseph D. Khoury, Elias Jabbour   +19 more
openaire   +2 more sources