Results 41 to 50 of about 79,614 (239)

Outcome of T‐cell acute lymphoblastic leukemia/lymphoma: Focus on near‐ETP phenotype and differential impact of nelarabine

American journal of hematology/oncology, 2021
Early T‐cell precursor acute lymphoblastic leukemia/lymphoma (ETP‐ALL/LBL) is characterized by a distinct immunophenotype (CD1a‐negative, CD8‐negative, CD5‐negative or weak‐positive
Kiyomi Morita, N. Jain, H. Kantarjian, Koichi Takahashi, Hong Fang, M. Konopleva, S. El Hussein, Feng Wang, N. Short, A. Maiti, K. Sasaki, G. Garcia-Manero, S. Konoplev, F. Ravandi, J. Khoury, E. Jabbour   +15 more
semanticscholar   +1 more source

Clinical and molecular characteristics of MEF2D fusion-positive B-cell precursor acute lymphoblastic leukemia in childhood, including a novel translocation resulting in MEF2D-HNRNPH1 gene fusion

Haematologica, 2019
Fusion genes involving MEF2D have recently been identified in precursor B-cell acute lymphoblastic leukemia, mutually exclusive of the common risk stratifying genetic abnormalities, although their true incidence and associated clinical characteristics ...
Kentaro Ohki, Nobutaka Kiyokawa, Yuya Saito, Shinsuke Hirabayashi, Kazuhiko Nakabayashi, Hitoshi Ichikawa, Yukihide Momozawa, Kohji Okamura, Ai Yoshimi, Hiroko Ogata-Kawata, Hiromi Sakamoto, Motohiro Kato, Keitaro Fukushima, Daisuke Hasegawa, Hiroko Fukushima, Masako Imai, Ryosuke Kajiwara, Takashi Koike, Isao Komori, Atsushi Matsui, Makiko Mori, Koichi Moriwaki, Yasushi Noguchi, Myoung-ja Park, Takahiro Ueda, Shohei Yamamoto, Koichi Matsuda, Teruhiko Yoshida, Kenji Matsumoto, Kenichiro Hata, Michiaki Kubo, Yoichi Matsubara, Hiroyuki Takahashi, Takashi Fukushima, Yasuhide Hayashi, Katsuyoshi Koh, Atsushi Manabe, Akira Ohara, for the Tokyo Children’s Cancer Study Group (TCCSG)   +38 more
doaj   +1 more source

Inotuzumab ozogamicin in clinical development for acute lymphoblastic leukemia and non-Hodgkin lymphoma

Biomarker Research, 2019
B cell acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) frequently express CD19, CD20 and CD22 on the cell surfaces. Immunotherapeutic agents including antibodies and chimeric antigen receptor T cells are widely studied in clinical ...
Amandeep Aujla, Ravijot Aujla, Delong Liu   +2 more
doaj   +1 more source

The Clinical Characteristics and Prognosis of AYA and Older Adult ETP-ALL/LBL: A Real-World Multicenter Study in China

Frontiers in Oncology, 2022
Early T-cell precursor (ETP) lymphoblastic leukemia/lymphoma is a high-risk T lymphoblastic leukemia/lymphoma (T-ALL/LBL) subgroup. We performed a real-world multicenter study to explore the clinical characteristics and prognosis of adolescent and young ...
Jinyan Xiao, Zihong Cai, Hao Wang, Xuekai Li, Biqi Zhou, Yujie Liu, Ying Wang, Peipei Xu, Peipei Xu, Li Wang, Li Wang, Depei Wu, Liping Dou, Liping Dou, Hongsheng Zhou, Hongsheng Zhou, Yang Xu, Yang Xu   +17 more
doaj   +1 more source

Aberrant positivity for CD79a in erythroid lineage cells – a finding observed in a subset of re-staging bone marrow trephine biopsies after treatment

Haematologica, 2007
Aberrant expression of CD79a has been reported in neoplastic cells in peripheral T cell lymphoma, T-cell acute lymphoblastic leukemia and acute myeloid leukemia (especially those with t(8;21)).
Rashpal Singh Flora, Finella Brito-Babapulle, Kikkeri N. Naresh   +2 more
doaj   +1 more source

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement

Haematologica, 2022
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r).
Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell   +39 more
doaj   +1 more source

Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

Definitions, 2020
A provisional entity describing precursor lymphoid neoplasms that express CD56 and immature T-cell markers, lack B-lymphoid and myeloid markers, and have the immunoglobulin and T-cell receptor genes in the germline configuration.

semanticscholar   +1 more source

Comparison of characteristics and outcomes on ETP-ALL/LBL and non-ETP ALL patients receiving allogeneic hematopoietic stem cell transplantation

Frontiers in Oncology, 2023
ObjectiveThis study aims to compare the characteristics of early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) and non-ETP ALL patients and the outcomes of these patients after allogeneic hematopoietic stem cell transplantation ...
Juan Chen, Juan Chen, Juan Chen, Li Liu, Runzhi Ma, Aiming Pang, Donglin Yang, Xin Chen, Jialin Wei, Yi He, Rongli Zhang, Weihua Zhai, Qiaoling Ma, Erlie Jiang, Mingzhe Han, Sizhou Feng   +15 more
doaj   +1 more source

Automated Detection of Acute Lymphoblastic Leukemia Subtypes from Microscopic Blood Smear Images using Deep Neural Networks [PDF]

arXiv, 2022
An estimated 300,000 new cases of leukemia are diagnosed each year which is 2.8 percent of all new cancer cases and the prevalence is rising day by day. The most dangerous and deadly type of leukemia is acute lymphoblastic leukemia (ALL), which affects people of all age groups, including children and adults.
arxiv  

Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia

Frontiers in Oncology, 2022
T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) arise from the transformation of precursor T-cells sharing common morphological and immunophenotypic features.
Giulia Veltri, F. Lovisa, G. Cortese, M. Pillon, E. Carraro, S. Cesaro, M. Provenzi, S. Buffardi, S. Francescato, A. Biffi, B. Buldini, V. Conter, V. Serafin, L. Mussolin   +13 more
semanticscholar   +1 more source