Results 81 to 90 of about 17,590 (203)

Prediction of B/T Subtype and ETV6–RUNX1 Translocation in Pediatric Acute Lymphoblastic Leukemia by Deep Learning Analysis of Giemsa‐Stained Whole Slide Images of Bone Marrow Aspirates

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Accurate determination of B/T‐cell lineage and the presence of the ETV6–RUNX1 translocation is critical for diagnosing acute lymphoblastic leukemia (ALL), as these factors influence treatment decisions and outcomes. However, these diagnostic processes often rely on advanced tools unavailable in low‐resource settings, creating a need
Arkadi Piven   +6 more
wiley   +1 more source

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Mandible infiltration as a clinical signal of extramedullary B-cell acute lymphoblastic leukemia/lymphoma in a child: Report of a rare case

open access: yesOral Oncology Reports
B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) is a type of malignancy involving uncontrolled proliferation of B-precursor lymphoid cells. This case report delineates B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) manifesting in the mandible and ...
Paulo Victor Mendes Penafort   +7 more
doaj  

Gastric Signet Ring Cell Carcinoma in a Helicobacter pylori‐Positive 10‐Year‐Old Boy: A Case Report and Literature Review

open access: yesCancer Science, Volume 116, Issue 8, Page 2064-2074, August 2025.
A case report and literature review of pediatric gastric signet ring cell carcinoma (GSRCC) suggest the potential role of H. pylori infection in the pathogenesis of pediatric GSRCC. ABSTRACT Gastric cancer is rare in pediatric populations, with gastric signet ring cell carcinoma (GSRCC) being an exceptionally infrequent subtype.
Xiaoxuan Li   +11 more
wiley   +1 more source

Necrotic Bone Involvement in an Adult Afflicted with B-Cell Precursor Acute Lymphoblastic Leukemia Mimicking Osteomyelitis: A Case Report

open access: yes대한영상의학회지, 2018
A 41-year-old female presented with complaint of left hip and buttock pain. Magnetic resonance imaging (MRI) showed multi-focal bone marrow signal intensity changes in left iliac bone, sacrum and femur with an area of necrosis. The primary radiological
Hae Won Kim   +3 more
doaj   +1 more source

CAR T Cells Beyond Cancer: Hope for Immunomodulatory Therapy of Infectious Diseases

open access: yesFrontiers in Immunology, 2019
Infectious diseases are still a significant cause of morbidity and mortality worldwide. Despite the progress in drug development, the occurrence of microbial resistance is still a significant concern.
Michelle Seif   +2 more
doaj   +1 more source

Maxilla Unilateral Swelling as the First Diagnostic Symptom of Acute Lymphoblastic Leukemia Relapse: A Case Report

open access: yesFrontiers in Dentistry, 2011
Acute Lymphoblastic Leukemia (ALL) is the most prevalent hematological malignant tumor during childhood. Unilateral infiltration into the gums is less prevalent and more often observed in the AML type.
M. Fallahinejad Ghajari   +2 more
doaj  

Immunophenotypic characterization of acute leukemia at a public oncology reference center in Maranhão, northeastern Brazil

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVES: The incidence of acute leukemia (AL) subtypes varies according to geographical distribution. The aim here was to determine the incidence of morphological and immunophenotypic AL subtypes in the state of Maranhão, Brazil, and to ...
Elda Pereira Noronha   +5 more
doaj   +1 more source

γδ T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature γδ T-Cell Malignancies

open access: yesCase Reports in Hematology, 2017
Gamma delta (γδ) T-cell antigen receptor (TCR) expression and its related T-cell differentiation are not commonly reported in T-cell acute lymphoblastic leukemia/lymphoma (T-ALL).
Eric X. Wei   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy