Results 81 to 90 of about 79,614 (239)
ОнкогематологияThe use of high-effective, multicomponent, risk-adopted chemoimmunotherapy schemes in children with Burkitt lymphoma reached advanced long-term progression-free survival over 90 % even for high risk patients.
T. T. Valiev +5 more
doaj +1 more source
Acute lymphoblastic leukemia may develop as a result of rapid transformation of a lymphoblast triggered by repeated bone-remodeling during bone-growth [PDF]
arXiv, 2018 Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are two major forms of leukemia that arise from lymphoid cells (LCs). ALL occurs mostly in children and CLL occurs mainly in old people. However, the Philadelphia-chromosome-positive ALL (Ph+-ALL) and the Ph-like ALL occur in both children and adults.
arxiv
Blood Advances, 2020 T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) represent malignancies that arise from the transformation of immature precursor T cells.
E. Kroeze +3 more
semanticscholar +1 more source
British Journal of Haematology, EarlyView.Using current standard‐of‐care tests used in clinical practice, 20%–30% of B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) patients remain unclassified. These patients are grouped into a heterogeneous category named B‐other ALL and are all treated with the same intensity. The application of RNA‐seq, together with the integration of standard‐of‐
Clara Vicente‐Garcés +12 more
wiley +1 more source
Explainable Techniques for Analyzing Flow Cytometry Cell Transformers [PDF]
arXiv, 2023 Explainability for Deep Learning Models is especially important for clinical applications, where decisions of automated systems have far-reaching consequences. While various post-hoc explainable methods, such as attention visualization and saliency maps, already exist for common data modalities, including natural language and images, little work has ...
arxiv
Organoids in Haematologic Research: Advances and Future Directions
Cell Proliferation, EarlyView.This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang +4 more
wiley +1 more source
Automated Detection of Acute Promyelocytic Leukemia in Blood Films and Bone Marrow Aspirates with Annotation-free Deep Learning [PDF]
arXiv, 2022 While optical microscopy inspection of blood films and bone marrow aspirates by a hematologist is a crucial step in establishing diagnosis of acute leukemia, especially in low-resource settings where other diagnostic modalities might not be available, the task remains time-consuming and prone to human inconsistencies.
arxiv
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Chemotherapy can have adverse gastrointestinal effects in dogs and people. The objective of this study was to assess the impact of vincristine and prednisolone/prednisone, as part of a CHOP chemotherapy [cyclophosphamide, hydroxydaunorubicin, oncovin (vincristine) and prednisolone/prednisone] protocol, on gastrointestinal dysbiosis in dogs ...
Juan Aragon +10 more
wiley +1 more source
Flow Cytometry in the Differential Diagnosis of Lymphocyte-Rich Thymoma From Precursor T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma [PDF]
, 2004 Shiyong Li +3 more
openalex +2 more sources
Orchard: building large cancer phylogenies using stochastic combinatorial search [PDF]
arXiv, 2023 Phylogenies depicting the evolutionary history of genetically heterogeneous subpopulations of cells from the same cancer, i.e., cancer phylogenies, offer valuable insights about cancer development and guide treatment strategies. Many methods exist that reconstruct cancer phylogenies using point mutations detected with bulk DNA sequencing.
arxiv