Results 101 to 110 of about 10,121,442 (237)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Enhanced Vehicle Dynamics and Safety through Tire–Road Friction Estimation for Predictive ELSD Control under Various Conditions of General Racing Tracks

Applied Sciences
This study focuses on the tire–road friction estimation for the predictive control strategy of electronically limited slip differential (ELSD) to improve the handling and acceleration performance of front-wheel drive cars, which typically suffer from ...
Seunghoon Woo, Seunguk Jeon, Eunhyek Joa, Donghoon Shin   +3 more
doaj   +1 more source

Multi-Step Predictive Current Control for NPC Grid-Connected Inverter

IEEE Access, 2019
Aiming at improving the quality of output current when the inverter is connected to the grid, this paper proposes a control strategy of neutral point clamped (NPC) grid-connected inverter based on radial basis function neural network (RBFNN) multi-step ...
Yunjun Yu, Xianzheng Wang
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Virtual position predictive control with system delay observer to improve PMLSM position tracking accuracy

IET Electric Power Applications
To improve the position tracking accuracy of permanent magnet linear synchronous motors (PMLSM), this paper introduces a virtual position predictive control (VPPC) with a system delay observer (SDO). Un‐like conventional position predictive control (CPPC)
Rongkun Wang, Congwei Su, Quankai Du, Qibin Xiong, Yujia Zhuang, Xinyi Zhang, Xinhua Guo   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Predictive control method with conduction mode detection to suppress input current distortion of three‐level power factor correction

IET Electric Power Applications
A novel predictive control method with conduction mode detection is proposed to suppress input current distortion of three‐level power factor correction (PFC) converters.
Xifeng Xie, Zeliang Shu, Rongxin Chen, Jianghong Yin, Chunxiang Ling   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Robust predictive control strategy for grid‐connected inverters with ultra‐local model based on linear matrix inequality

IET Power Electronics
To address the issue of poor robustness in the model predictive control of grid‐connected inverters due to disturbances in load model parameters, this article developed an ultra‐local model robust predictive controller based on Linear Matrix Inequality ...
Chunxi Liu, Fangrui Hong, Zhile Liu, Li Zhou, Xuanxu Jin, Zhiwei Lin   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source