Results 241 to 250 of about 4,798,414 (293)

A cell-based kinetic framework enables TCR specificity prediction. [PDF]

open access: yesSignal Transduct Target Ther
Culka M   +12 more
europepmc   +1 more source

Predictive functional assay-based classification of PMS2 variants in Lynch syndrome

open access: yesHuman Mutation, 2022
The large majority of germline alterations identified in the DNA mismatch repair (MMR) gene PMS2, a low-penetrance gene for the cancer predisposition Lynch syndrome, represent variants of uncertain significance (VUS). The inability to classify most VUS interferes with personalized healthcare.
Bryony A Thompson   +2 more
exaly   +6 more sources

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