Results 81 to 90 of about 158,711 (303)
Statistical methods for automated drug susceptibility testing: Bayesian minimum inhibitory concentration prediction from growth curves [PDF]
Determination of the minimum inhibitory concentration (MIC) of a drug that prevents microbial growth is an important step for managing patients with infections.
Clyde, Merlise A. +7 more
core +3 more sources
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Effect of pH and temperature on Shiga toxin-producing Escherichia coli O157:H7 isolated from bovine reservoir [PDF]
The aim of this study was to evaluate the individual and combined effect of pH (between 4.0 and 7.0) and storage temperature (between 6 and 35°C) on two wild-type E. coli O157:H7 (STEC 902 and STEC 2004) strains.
BIANCA M.F. SILVA +5 more
doaj +1 more source
Sputum microbiology predicts health status in COPD
Spontaneous sputum production occurs in a subset of COPD patients; however, its clinical relevance has not been established. Differences in health status and clinical outcomes between patients with and without positive sputum cultures are unknown.To compare clinical characteristics and health status of spontaneous sputum producers with a positive ...
Braeken, D.C.W. +7 more
openaire +4 more sources
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu +13 more
wiley +1 more source
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu +13 more
wiley +1 more source
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
The primary objective of this study was to investigate the behavior of Listeria monocytogenes (L. monocytogenes) on fresh-cut cucumbers. Fresh-cut cucumber samples were inoculated with a mixture of six strains of L. monocytogenes.
Ke Feng +3 more
doaj +1 more source
Evaluation of matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) for the Identification of Group B Streptococcus. [PDF]
Objective Group B Streptococcus (GBS) is a leading cause of neonatal meningitis and sepsis worldwide. Intrapartum antibiotics given to women carrying GBS are an effective means of reducing disease in the first week of life.
Chalker, V +6 more
core +1 more source
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source

