Results 101 to 110 of about 7,717,977 (381)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Digital hand‐held arthrometry is a reliable and accurate adjunct for diagnosing acute anterior cruciate ligament tears

Journal of Experimental Orthopaedics
Purpose To evaluate the intrarater reliability and predictive validity of Lachmeter® measurements for diagnosing acute anterior cruciate ligament (ACL) tears, and to propose diagnostic thresholds.
Richard Norris, Alan Price, Thomas W. Maddox, William Boswell, Cronan Kerin, Rachel A. Oldershaw   +5 more
doaj   +1 more source

Personality traits and emotional intelligence as predictors of teachers' psychological well-being [PDF]

Psihološka Obzorja, 2009
We examined predictive validity of the Big Five personality traits and three dimensions of emotional intelligence (EI) regarding psychological well-being on the sample of primary and highschool teachers.
Andreja Avsec, Polona Masnec, Luka Komidar   +2 more
doaj  

Vocal Audiometry in Hearing Aid Outcome Measurements [PDF]

, 2009
Single word repetition in quiet differs drastically from everyday conversation, raising validity issues when quality-of-life-type predictions are made starting from classic vocal audiometry.
Corthals, Paul, De Bont, Marijke, Degryse, Annika   +2 more
core  

The predictive validity of the Living Goods selection tools for community health workers in Kenya : cohort study [PDF]

, 2018
Background Ensuring that selection processes for Community Health Workers (CHWs) are effective is important due to the scale and scope of modern CHW programmes. However they are relatively understudied.
Griffiths, Frances, Lilford, Richard, Ngechu, Ruth, Taylor, Celia A., Wroe, Emily   +4 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Dedication [PDF]

, 2001
OBJECTIVES: The aims of this study were to examine and compare the predictive validity of 4 risk assessment scales used for the prediction of pressure ulcer (PrU) development and to identify risk factors.
Källman, Ulrika, Lindgren, Margareta
core   +3 more sources

Predictive validity in drug discovery: what it is, why it matters and how to improve it

Nature reviews. Drug discovery, 2022
J. Scannell, J. Bosley, J. Hickman, G. Dawson, H. Truebel, Guilherme S Ferreira, Duncan Richards, J. M. Treherne   +7 more
semanticscholar   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Intra-Session Reliability and Predictive Value of Maximum Voluntary Isometric Contraction for Estimating One-Repetition Maximum in Older Women: A Randomised Split-Sample Study

Journal of Functional Morphology and Kinesiology
Background: Ageing is associated with a progressive decline in muscle strength, particularly in the lower limbs, which compromises functional independence.
José Aldo Hernández-Murúa, Ena Monserrat Romero-Pérez, Jorge Luis Guajardo-Cruztitla, Blas Sinahí Madrigal Olivares, Ángel Gallego-Selles, Diego González-Martín, Francisca Reyes-Merino, Nidia Sánchez-García, José Antonio de Paz   +8 more
doaj   +1 more source