Results 181 to 190 of about 18,186,110 (393)

Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials †

Annals of Oncology, 2017
D. Arnold, B. Lueza, J. Douillard, M. Peeters, H. Lenz, A. Venook, V. Heinemann, E. Cutsem, J. Pignon, J. Tabernero, Andrés Cervantes, Andrés Cervantes, F. Ciardiello   +12 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Análise comparativa entre tuberculose multirresistente e tuberculose extensivamente resistente - Epidemiologia e factores preditivos Comparative analysis of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis - Epidemiology and predictive factors

Revista Portuguesa de Pneumologia, 2008
Introdução: A tuberculose extensivamente resistente (TBXDR) define -se como uma forma de tuberculose multirresistente (TBMR) com resistências adicionais às fluoroquinolonas e, pelo menos, a um dos antibacilares injectáveis seguintes: amicacina ...
Ana Sofia Vilariça, Carlos Gomes, Jaime Pina   +2 more
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Value of Preoperative Indocyanine Green Clearance Test for Predicting Post-Hepatectomy Liver Failure in Noncirrhotic Patients

, 2017
Cem İbiş, Doğan Albayrak, İbrahim Tayfun Şahiner, Yiğit Soytaş, Başak Gürtekin, Nükhet Sivrikoz   +5 more
openalex   +2 more sources

MP28-19 SETTING THE BAR: A 4KSCORE OF 7.5% PROVIDES HIGH SENSITIVITY AND NEGATIVE PREDICTIVE VALUE FOR DETECTING AND RULING OUT SIGNIFICANT PROSTATE CANCER [PDF]

, 2019
Amit S. Bhattu, Yan Dong, Alexander Kong, Stephen Zappala, Dipen J. Parekh, Sanoj Punnen   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Predictive value of inflammatory Cytokines in preeclampsia

, 2015
Madhur Gupta, Suresh T. Chari
openalex   +2 more sources

Arterial spin labeling-based Z-maps have high specificity and positive predictive value for neurodegenerative dementia compared to FDG-PET [PDF]

, 2017
David Fällmar, Sven Haller, Johan Lilja, Torsten Danfors, Lena Kilander, Nelleke Tolboom, Karl Egger, Elias Kellner, Philip M. Croon, Sander C.J. Verfaillie, Bart N.M. van Berckel, Rik Ossenkoppele, Frederik Barkhof, Elna‐Marie Larsson   +13 more
openalex   +1 more source