Results 111 to 120 of about 1,539,986 (394)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Use of Skin Testing Screening and Desensitization Before the First Exposure of Rituximab
Lisha Li,1 Lianglu Wang,1 Kai Guan,1 Jun Liu,1 Daobin Zhou,2 Yanbin Zhang,2 Yan Zhang2 1Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Precision ...
Li L +6 more
doaj
How Much Can Outlook Forecasts be Improved? An Application to the U.S. Hog Market [PDF]
This study investigates the predictability of outlook hog price forecasts released by Iowa State University relative to alternative market and time-series forecasts.
Colino, Evelyn V. +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Jolt accentuation of headache: can this maneuver rule out acute meningitis?
Objective Acute meningitis is a medical emergency and its accurate diagnosis could help physicians to accelerate treatment and reduce the mortality and morbidity of patients.
Shirin Afhami +2 more
doaj +1 more source
Poor positive predictive value of influenza‐like illness criteria in adult transplant patients: a case for multiplex respiratory virus
Jonathan Claus +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Glycosylated haemoglobin (HbA1c) and cortisol levels on admission to intensive care as predictors of outcome [PDF]
Objective: To evaluate the predictive value of glycosylated haemoglobin and cortisol on admission, in critical care patients. Design: Prospective, observational, single centre study. Setting: 14 bedded Intensive care unit of a tertiary-level university
Abela, Carmel J. +5 more
core
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Artificial intelligence (AI) systems are already being used in various healthcare areas. Similarly, they can offer many advantages in hospital emergency services.
Nicolás J. Garrido +5 more
doaj +1 more source

