Results 201 to 210 of about 1,276,953 (303)

Developing and validating a machine learning model for predicting post-thrombolysis seizures in acute ischemic stroke. [PDF]

Medicine (Baltimore)
Jia L, Hu Y, Jin G, Zhou Z.
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Motor and Dexterity Assessments as Predictors of Functional Independence in Post-stroke Patients. [PDF]

Cureus
Šabanagić-Hajrić S, Mahmutbegovic N, Hasanbegovic E, Al-Tawil A, Al-Tawil A, Mukinovic D.   +5 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Comparative performance of standalone E6/E7 mRNA testing versus a combined DNA genotyping and viral load assay for detecting cervical high-grade lesions: a retrospective paired study. [PDF]

Am J Transl Res
Wang J, Wang L, Bu F, Chen S, Zhang R, Liu X, Ding H, Chen Y.   +7 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Positive predictive value metrics for multicancer detection tests. [PDF]

J Med Screen
Pinsky PF, LeeVan EM, Patriotis C, Rubinstein WS.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Task-shifting in eye health: Assessing the accuracy and feasibility of community worker-led vision screening. MEDiS report # 2. [PDF]

Indian J Ophthalmol
Rogye A, Singh AK, Nicholson M, Krishnan R, Das T, MEDiS Working Group , Murthy S, Das T, Krishnan R, Nicholson M, Rogye A, Sharma T, Setia M, Singh AK, Gawade S, Kumari A, Murudkar J.   +16 more
europepmc   +1 more source

Predictive Values and Efficiency of Laboratory Testing [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1986
openaire   +1 more source