Results 71 to 80 of about 936,691 (247)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Annals of Global HealthBackground: The world still grapples with alarming maternal mortality rates, particularly in developing nations, including Nigeria. Annual global deaths exceed 500,000, predominantly in developing countries (99%) and sub‑Saharan Africa (over 50%), where ...
Esther Oluwakemi Oluwole +3 more
doaj +1 more source
Beyond conformal predictors: Adaptive Conformal Inference with confidence predictors
Pattern Recognition28 pages, 5 ...
Johan Hallberg Szabadváry +1 more
openaire +2 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Frontiers in Global Women's HealthBackgroundThe use of modern contraceptives by married Ethiopian women has increased over the past 15 years. Despite a few studies reporting different predictors of satisfaction with family planning services, there is a lack of nationwide data showing the
Yeshiwas Ayale Ferede +2 more
doaj +1 more source
DAIMI Report Series, 2000 The most important theoretical tool in connection with machine learning is the bias/variance decomposition of error functions. Together with Tom Heskes, I have found the family of error functions with a natural bias/variance decomposition that has target independent variance.
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Parietal alpha and theta power predict cognitive training gains in middle-aged adults
Frontiers in Aging NeuroscienceResearch on executive functions training shows inconsistent outcomes, with factors like age, baseline cognitive abilities, and personality traits implicated as predictive of training gains, while limited attention has been given to neurophysiological ...
Luka Juras +2 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Personification of the approaches to reperfusion therapy of ischemic stroke
Анналы клинической и экспериментальной неврологии, 2017 Introduction. Systemic thrombolytic therapy using recombinant tissue plasminogen activator (rtPA) is the gold standard of reperfusion therapy in certainpatients with ischemic stroke during the first 4.5 h after stroke onset. Objective.
Maksim A. Domashenko +5 more
doaj +1 more source