Results 91 to 100 of about 1,308,374 (305)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Skim yoghurt with microbial transglutaminase: evaluation of consumer acceptance
CyTA - Journal of Food, 2019 The decrease in the fat content of yoghurt causes sensory modifications. Microbial transglutaminase (TG) has been proposed as an alternative for reducing the problems caused by the fat reduction. This work deals with the evaluation of the sensory profile,
Belén García-Gómez +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Stochastic Revealed Preference and Rationalizability [PDF]
This paper explorers rationalizability issues for finite sets of observations of stochastic choice in the framework introduced by Bandyopadhyay et al. (JET, 1999). Is is argued that a useful approach is to consider indirect preferences on budgets instead
Jan Heufer
core
Patient Preference and AdherenceXiaoying Liu,1 Ian P Smith,2 Ellen M Janssen,3 Carol Mansfield4 1Population Studies Center, University of Pennsylvania, Philadelphia, PA, USA; 2Interventional Oncology, Johnson & Johnson External Innovation, New Brunswick, NJ, USA; 3Global ...
Liu X, Smith IP, Janssen EM, Mansfield C
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A New Type of Preference Reversal [PDF]
The classic preference reversal phenomenon arises in a comparison between a choice and a matching task. We present a new type of preference reversal which is entirely choice-based.
Jose Luis Pinto-Prades, Han Bleichrodt
core
A revealed preference analysis of the rational addiction model [PDF]
We provide a revealed preference analysis of the rational addiction model. The revealed preference approach avoids the need to impose an, a priori unverifiable, functional form on the underlying utility function.
Ewout VERRIEST, Thomas DEMUYNCK
core +2 more sources
US Retina Specialists’ Preferences for Geographic Atrophy Treatment
Clinical OphthalmologyKarl Csaky,1 Anthony M Pepio,2 Caitlin Thomas,3 Bennett Levitan,4 Seema Garg,5 Nguyet Tran,4 Ilan Irony,6 Nicolas Krucien,3 Anastasia Doldos,3 Jennifer A Whitty3 1Ophthalmology Department, Retina Foundation of the Southwest, Dallas, TX, USA; 2Research ...
Csaky K +9 more
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