Results 101 to 110 of about 1,308,374 (305)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Therapy preference [PDF]

open access: yes, 2021
Section A A review of the literature consisting of a systematic search and narrative review to determine i) whether adults in the general population have psychotherapy preferences, and ii) whether there are specific individual characteristics that ...
Nielsen, A.
core  

On the Role of Preference Variance in Preference Optimization

open access: yesCoRR
Direct Preference Optimization (DPO) has emerged as an important approach for learning from human preferences in aligning large language models (LLMs). However, collecting human preference data is costly and inefficient, motivating methods to reduce the required annotations.
Jiacheng Guo   +4 more
openaire   +2 more sources

Sequential effects in preference decision: Prior preference assimilates current preference

open access: yesPLOS ONE, 2017
An important factor affecting preference formation is the context in which that preference decision takes place. The current research examined whether one's preference formed for a previously presented stimulus influences the processing of a subsequent preference decision, henceforth referred to as the preference sequence effect.
Seah Chang, Chai-Youn Kim, Yang Seok Cho
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Arboreal Ant Assemblages Respond Differently to Food Source and Vegetation Physiognomies: a Study in the Brazilian Atlantic Rain Forest

open access: yesSociobiology, 2013
This study aimed to analyze assemblages of arboreal ants in different vegetation physiognomies within the Tropical Moist Forest (Atlantic Rain Forest) domain.
Janete Jane Resende   +4 more
doaj  

EEG Beta Oscillations in the Temporoparietal Area Related to the Accuracy in Estimating Others' Preference

open access: yesFrontiers in Human Neuroscience, 2018
Humans often attempt to predict what others prefer based on a narrow slice of experience, called thin-slicing. According to the theoretical bases for how humans can predict the preference of others, one tends to estimate the other's preference using a ...
Jonghyeok Park   +4 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Preferences and Priorities for Relapsed Multiple Myeloma Treatments Among Patients and Caregivers in the United States

open access: yesPatient Preference and Adherence, 2022
Daniel Auclair,1,* Carol Mansfield,2,* Mark A Fiala,3,* Ajai Chari,4 Craig E Cole,5 Jonathan L Kaufman,6 Gregory J Orloff,7 David S Siegel,8 Jeffrey A Zonder,9 Brennan Mange,2 Jennifer Yesil,1 Mehul Dalal,10 Joseph R Mikhael11 1Department of ...
Auclair D   +12 more
doaj  

HelpSteer2-Preference: Complementing Ratings with Preferences

open access: yesCoRR
Accepted to ICLR 2025; 28 pages, 3 ...
Zhilin Wang   +7 more
openaire   +3 more sources

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