Results 81 to 90 of about 767,649 (269)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Effects of Musical Fit on Choice Between Competing Pairs of Cultural Products

open access: yesEmpirical Musicology Review, 2010
Previous studies have claimed that music can prime the selection of certain products and influence consumers’ propensity to spend because it activates related knowledge of the world and subsequently raises the salience of certain products and behaviors ...
Joanne P. S. Yeoh, Adrian C. North
doaj   +1 more source

Disentangling revealed preference from rationalization by a preference

open access: yesEconomics Letters, 2023
The weak axiom of revealed preference (WARP) ensures that the revealed preference (i) is a preference relation (i.e., it is complete and transitive) and (ii) rationalizes the choices. However, when WARP fails, either one of these two properties is violated, but it is unclear which one it is. We provide an alternative characterization of WARP by showing
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Yield, silage quality, and feeding preference of late‐summer sown pearl millet (Cenchrus americanus (L.) Morrone) in Southern Kyushu

open access: yesGrassland Research
Background Pearl millet is characterized by its high dry matter (DM) yields with a high moisture content, which makes it difficult to process as silage. Methods Pearl millet was sown in mid‐September for 3 years to examine its growth, DM yields in early ...
Genki Ishigaki   +5 more
doaj   +1 more source

Degree of fear of needles and preferred allergy immunotherapy treatment among children with allergic rhinitis: caregiver survey results

open access: yesFrontiers in Pediatrics
IntroductionA child's fear of needles may impact the preferred route of allergy immunotherapy (AIT) when choosing between subcutaneous immunotherapy (allergy shots) or sublingual immunotherapy (SLIT). A survey was conducted to understand caregiver health-
Karen Rance   +5 more
doaj   +1 more source

An Evidential Aggregation Method of Intuitionistic Fuzzy Sets Based on Belief Entropy

open access: yesIEEE Access, 2019
Intuitionistic fuzzy sets (IFSs) are essential in the multi-criteria decision making (MCDM) under uncertain environment. However, how to reasonably aggregate them with considering the uncertainty contained in the IFSs is still an open issue.
Zeyi Liu, Fuyuan Xiao
doaj   +1 more source

Preference Anomalies, Preference Elicitation and the Discovered Preference Hypothesis

open access: yesEnvironmental and Resource Economics, 2005
There is wide-ranging evidence, much of it deriving from economics experiments, of ‘anomalies’ in behaviour that challenge standard preference theories. This paper explores the implications of these anomalies for preference elicitation methods. Because methods that are used to inform public policy, such as contingent valuation, are based on standard ...
Jacinto Braga, Chris Starmer
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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