Results 71 to 80 of about 1,308,374 (305)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On the priority vector associated with a fuzzy preference relation and a multiplicative preference relation. [PDF]
We propose two straightforward methods for deriving the priority vector associated with a fuzzy preference relation. Then, using transformations between multiplicative preference relations and fuzzy preference relations, we study the relationships ...
Matteo Brunelli, Michele Fedrizzi
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Intake pattern and feed sorting of beef cattle fed different sources of corn in a feedlot
Revista Colombiana de Ciencia Animal ReciaThe objective of this experiment was to determine the feed intake pattern and feed sorting of 30 Nelore males finished in a feedlot fed diets based on three different sources of corn: whole crop silage (WCS), high moisture corn (HMC) or corn grain (CG).
Matheus Silva Rodrigues +3 more
doaj +1 more source
Preferensi Masyarakat terhadap Ruang Kota sebagai Tempat Relaksasi
RUAS, 2020 People who live in urban areas tend to have a higher stress level than those who live in rural areas. Level of stress can be prevented and diminished through the establishment of urban relaxation spaces within the city.
Mutia Ayu Cahyaningtyas, Hanson E Kusuma
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Final report of the Task Force on Sexual Preference
, 1978 At head of title: State of Oregon, Department of Human Resources.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source