Results 61 to 70 of about 6,333 (261)

Paschen–Back effect modulation of SO4 2- hydration in magnetized electrolyte toward dendrite-free Zn-ion batteries

Nature Communications
Tuning anionic solvation structures and dynamic processes at solid–liquid interfaces is critical yet challenging for stabilizing Zn metal negative electrodes in Zn-ion batteries, particularly due to the issue of dendrite formation and hydrogen evolution ...
Xiayan Yao, Zhi Wang, Jianwei Guo, Guoyu Qian, Hongchen Wang, Xuzhong Gong, Dong Wang   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Weakly dissociated lithium salt decouples solvent–anion interfacial dynamics for wide-temperature lithium-ion batteries [PDF]

EES Batteries
Developing lithium-ion batteries (LIBs) operable across extreme temperatures (−40 to 60 °C) is imperative for electric vehicles and space technologies, yet hindered by incompatible interphasial requirements: cathode–electrolyte interphase (CEI ...
Shaoyun Zhou, Zetai Xu, Chaonan Wang, Chao Tang, Junhua Jian, Meirong Wang, Hong-Bin Yao, Hongchang Jin, Yuhao Lu, Hengxing Ji   +9 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

2,5-PRODAN Derivatives as Highly Sensitive Sensors of Low Solvent Acidity

Molecules, 2014
Two 5-acyl-2-dimethylaminonaphthalene derivatives, one with a propionyl group and the other with a fused cyclohexanone ring, are investigated as sensors of H-bond-donating ability in protic solvents of low solvent acidity.
Alexandra H. Yoon, Laura C. Whitworth, Joel D. Wagner, Christopher J. Abelt   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Impact of non-covalent interactions on the solvation of ovalbumin in an aqueous environment of different pHs: Thermodynamic and diffusion studies

Heliyon
The solvation behavior of protein is an important factor in protein-based food products. In the present study, the xylitol (XY) - ovalbumin (OVN) interaction in an aqueous solution of different pH conditions is analyzed in two methods. In one method, the
Swenthira K, Agalya P, Sasikumar P, Thafasalijyas Vayalpurayil, Mohamed Abbas, Velusamy V   +5 more
doaj   +1 more source

Preferential Solvation Study of Rosuvastatin in the {PEG400 (1) + Water (2)} Cosolvent Mixture and GastroPlus Software-Based In Vivo Predictions. [PDF]

ACS Omega, 2023
Hussain A, Afzal O, Yasmin S, Haider N, Altamimi ASA, Martinez F, Acree WE, Ramzan M.   +7 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Effect of N-Methyl-pyrrolidone (NMP) on the Equilibrium Solubility of Meloxicam in Aqueous Media: Correlation, Dissolution Thermodynamics, and Preferential Solvation. [PDF]

ACS Omega, 2022
Tinjacá DA, Martínez F, Almanza OA, Jouyban A, Acree WE.   +4 more
europepmc   +1 more source