Results 41 to 50 of about 5,466 (262)

Simulation and mathematical analysis of L-Cysteine's transfer properties and solvation behavior in mixed water–alcohol solutions

Chemical Thermodynamics and Thermal Analysis
We investigated preferential solvation of L-Cystine (L-Cys) in two aqueous co-solvent systems (methanol (MeOH) and ethanol (EtOH)), utilizing the mole percentage solubility data provided.
Adel Noubigh, Rafik Tayeb, Amani A.S. Abdelaziz   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Stereoisomeric engineering mediated zinc metal electrodeposition: Critical balance of solvation and adsorption capability

Advanced Powder Materials
The exceptional electrochemical performance of zinc anodes is frequently impeded by inadequate deposition kinetics and interfacial chemistry. Herein, we introduce the stereoisomerism to inform the balanced selection of electrolyte additives, taking into ...
Wen Liu, Qiwen Zhao, Ruheng Jiang, Xuyan Ni, Tiancheng You, Canglong Li, Yanzi Deng, Bingang Xu, Yuejiao Chen, Libao Chen   +9 more
doaj   +1 more source

Activation of Electrophile/Nucleophile Pair by a Nucleophilic and Electrophilic Solvation in a SNAr Reaction

Frontiers in Chemistry, 2018
Nucleophilic aromatic substitution reactions of 4-chloroquinazoline toward aniline and hydrazine were used as a model system to experimentally show that a substrate bearing heteroatoms on the aromatic ring as substituent is able to establish ...
Bruno Sánchez, Cristian Calderón, Ricardo A. Tapia, Renato Contreras, Paola R. Campodónico   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Preferential solvation of xylitol in ethanol + water co-solvent mixtures according to the IKBI and QLQC methods

Revista Colombiana de Química, 2014
The preferential solvation parameters, i.e., the differences between the local around the solute and bulk mole fractions of the solvents in solutions of xylitol in ethanol + water binary mixtures are derived from their thermodynamic properties by means ...
Daniel Delgado, Edgar vargas, Fleming Martínez   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Effect of urea on biomimetic aggregates

Brazilian Journal of Medical and Biological Research, 1997
The effect of urea on biomimetic aggregates (aqueous and reversed micelles, vesicles and monolayers) was investigated to obtain insights into the effect of the denaturant on structured macromolecules.
F.H. Florenzano, M.J. Politi
doaj   +1 more source