Results 1 to 10 of about 14,435,632 (168)

Drug Solubility Correlation Using the Jouyban–Acree Model: Effects of Concentration Units and Error Criteria [PDF]

Molecules, 2022
An important factor affecting the model accuracy is the unit expression type for solute and solvent concentrations. One can report the solute and solvent concentration in various units and compare them with various error scales.
Elaheh Rahimpour, Sima Alvani-Alamdari, William E. Acree, Abolghasem Jouyban   +3 more
doaj   +6 more sources

Viscosity Investigations on the Binary Systems of (1 ChCl:2 Ethylene Glycol) DES and Methanol or Ethanol [PDF]

Molecules, 2021
In this study, the viscosity behavior of two mixtures of Ethaline (1 ChCl:2 ethylene glycol) with either methanol or ethanol were investigated over the temperature range of 283.15–333.15 K at atmospheric pressure.
Reza Haghbakhsh, Ana Rita C. Duarte, Sona Raeissi   +2 more
doaj   +2 more sources

Experimental measurement, thermodynamic analysis, and mathematical modeling for budesonide solubility in 1-propanol + water mixtures at T = (293.2 to 313.2) K [PDF]

BMC Chemistry
Budesonide (BDS) a steroid-based anti-inflammatory drug widely prescribed for various diseases, has a low aqueous solubility. In this study, we investigated cosolvency approach to study the thermodynamic specifications related to the solubility of BDS at
Esmaeil Mohammadian, Mina Dashti, Fleming Martinez, Abolghasem Jouyban   +3 more
doaj   +2 more sources

Investigation of the solubility and thermodynamics of salicylic acid in 2-propanol and ethylene glycol/propylene glycol binary solvent mixtures at (293.15 to 313.15) K [PDF]

BMC Chemistry
This study aimed to measure both the solubility and thermodynamics of salicylic acid in binary solvent mixtures of (2-propanol + ethylene glycol) and (2-propanol + propylene glycol) at different temperatures in the range of 293.2–313.2 K.
Fatemeh Dabagh, Fatemeh Khalili, Aynaz Zarghampour, Salar Hemmati, Jalal Hanaee, Elaheh Rahimpour, Abolghasem Jouyban   +6 more
doaj   +2 more sources

Drug-delivery oriented solubility enhancement of curcumin in choline chloride-based acidic deep eutectic solvents: thermodynamic analysis and MCF-7 cytotoxicity assessment [PDF]

BMC Chemistry
Curcumin is a bioactive compound with well-established chemopreventive and anticancer properties, but its pharmaceutical application is limited by extremely low aqueous solubility and poor formulation-dependent bioavailability.
Mohammad Khorsandi, Hemayat Shekaari, Parisa Akbarzadeh Gondoghdi, Soheil Abbaspour-Ravasjani, Hamed Hamishehkar   +4 more
doaj   +2 more sources

Densities, Viscosities, Refractive Indices and Sound Speeds of Acetophenone with Methylacetate at Different Temperatures

E-Journal of Chemistry, 2012
Densities, viscosities, refractive indices and ultrasonic velocities of the binary mixtures of Acetophenone with Methyl acetate were measured over the entire mole fractions at (303.15, 313.15 and 323.15) K.
K. Saravanakumar, R. Baskaran, T. R. Kubendran   +2 more
doaj   +2 more sources

Solubility Data of the Bioactive Compound Piperine in (Transcutol + Water) Mixtures: Computational Modeling, Hansen Solubility Parameters and Mixing Thermodynamic Parameters [PDF]

Molecules, 2020
The solubility values and thermodynamic parameters of a natural phytomedicine/nutrient piperine (PPN) in Transcutol-HP (THP) + water combinations were determined. The mole fraction solubilities (xe) of PPN in THP + water combinations were recorded at T =
Faiyaz Shakeel, Nazrul Haq, Sultan Alshehri   +2 more
doaj   +2 more sources

Solubility, Hansen Solubility Parameters and Thermodynamic Behavior of Emtricitabine in Various (Polyethylene Glycol-400 + Water) Mixtures: Computational Modeling and Thermodynamics [PDF]

Molecules, 2020
This study was aimed to find out the solubility, thermodynamic behavior, Hansen solubility parameters and molecular interactions of an antiviral drug emtricitabine (ECT) in various “[polyethylene glycol-400 (PEG-400) + water]” mixtures. The solubility of
Faiyaz Shakeel, Nazrul Haq, Ibrahim A. Alsarra, Sultan Alshehri   +3 more
doaj   +2 more sources

Effect of 2-hydroxyethylammonium carboxylate protic ionic liquids on the solubility and cytotoxicity of indomethacin [PDF]

BMC Chemistry
Recently, there is a particular interest to utilize protic ionic liquids (PILs) in drug solubility. This study is exploring the effect of three protic ionic liquids (PILs) based on 2-hydroxyethylammonium carboxylate [2-hydroxyethylammonium acetate (MEAA),
Parisa Akbarzadeh Gondoghdi, Mohammad Khorsandi, Masumeh Mokhtarpour, Hemayat Shekaari, Hamed Hamishehkar   +4 more
doaj   +2 more sources

Solubility Characteristics of Acetaminophen and Phenacetin in Binary Mixtures of Aqueous Organic Solvents: Experimental and Deep Machine Learning Screening of Green Dissolution Media [PDF]

Pharmaceutics, 2022
The solubility of active pharmaceutical ingredients is a mandatory physicochemical characteristic in pharmaceutical practice. However, the number of potential solvents and their mixtures prevents direct measurements of all possible combinations for ...
Piotr Cysewski, Tomasz Jeliński, Maciej Przybyłek, Wiktor Nowak, Michał Olczak   +4 more
doaj   +2 more sources