Results 121 to 130 of about 199,923 (254)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Psychopathy traits and their link to emotion recognition impairments in conduct disorder

JCPP Advances, EarlyView.
Abstract Background Neurocognitive models suggest that callous‐unemotional (CU) traits in youths with conduct disorder (CD) are linked to emotion recognition impairments, particularly in identifying distress emotions like fear and sadness. However, CD may be accompanied by grandiose‐manipulative (GM) and/or impulsive‐irresponsible (II) traits in ...
Gregor Kohls, Anka Bernhard, Graeme Fairchild, Christina Stadler, Lucres Jansen, Stephane A. De Brito, Veit Roessner, Christine M. Freitag, Kerstin Konrad, Erik M. Elster   +9 more
wiley   +1 more source

Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression. [PDF]

J Neurochem
Uliana DL, Grace AA.
europepmc   +1 more source

Neural correlates of resilience to trauma during adolescence: A multi‐modal study

JCPP Advances, EarlyView.
Abstract Background Understanding resilience mechanisms is important for advancing early intervention strategies, yet research on the neurobiology of resilience in adolescents is limited. The present study examined the brain structural and resting‐state functional connectivity (rsFC) correlates of resilience to internalizing and externalizing symptoms ...
Lu Zhang, Vanessa L. Cropley, Divyangana Rakesh, Sarah Whittle   +3 more
wiley   +1 more source

Prefrontal Cortex [PDF]

, 2020
openaire   +2 more sources

Formation of task representations and replay in mouse medial prefrontal cortex. [PDF]

Elife
Shabani H, Muysers H, Yiu YH, Sauer JF, Bartos M, Leibold C.   +5 more
europepmc   +1 more source

Reward processing in children with affective dysregulation

JCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner, Francisca Giller, Nathalie Holz, Anna Kaiser, Christine Igel, Sarah Hohmann, Manfred Döpfner, Veit Roessner, Christian Beste, Tobias Banaschewski, Daniel Brandeis, on behalf ofthe ADOPT Consortium   +11 more
wiley   +1 more source

Role of prefrontal cortex in freezing of gait in Parkinson's disease: mechanisms and neuroimaging evidence. [PDF]

Front Neurol
Ji Q, Mei S, Cai L, Elmadhoun O, Ding Y, Geng X.   +5 more
europepmc   +1 more source

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca, Gianmauro Palombelli, Nicola Vanacore, Rossella Canese   +3 more
wiley   +1 more source

Cognition improvement in U.S. veterans undergoing treatment for posttraumatic stress disorder: Secondary analyses from a randomized controlled trial

Journal of Traumatic Stress, EarlyView.
Abstract Cognitive dysfunction is a hallmark of posttraumatic stress disorder (PTSD). Although treatments effectively reduce core PTSD symptoms, limited research has examined whether associated cognitive impairments improve following treatment.
Zulkayda Mamat, Danielle C. Mathersul, Peter J. Bayley   +2 more
wiley   +1 more source