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Current Biology, 2022
The prefrontal cortex is a well-studied but, in terms of understanding what it is for, deeply divisive part of the brain located at the front of the head. Perhaps the least controversial feature of the prefrontal cortex is its complexity. The prefrontal cortex is anatomically, functionally, and computationally complex.
Matthew V, Chafee, Sarah R, Heilbronner
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The prefrontal cortex is a well-studied but, in terms of understanding what it is for, deeply divisive part of the brain located at the front of the head. Perhaps the least controversial feature of the prefrontal cortex is its complexity. The prefrontal cortex is anatomically, functionally, and computationally complex.
Matthew V, Chafee, Sarah R, Heilbronner
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2006
Abstract This chapter describes the isotope injections that were placed in the prefrontal cortex of four rhesus monkeys. It analyzes the resulting association, striatal, commissural, and subcortical fiber trajectories, as well as the cortical and subcortical terminations. The injections were in the medial surface of the prefrontal cortex
Jeremy D. Schmahmann, Deepak N. Pandya
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Abstract This chapter describes the isotope injections that were placed in the prefrontal cortex of four rhesus monkeys. It analyzes the resulting association, striatal, commissural, and subcortical fiber trajectories, as well as the cortical and subcortical terminations. The injections were in the medial surface of the prefrontal cortex
Jeremy D. Schmahmann, Deepak N. Pandya
+5 more sources
Evolution of prefrontal cortex
Neuropsychopharmacology, 2021Subdivisions of the prefrontal cortex (PFC) evolved at different times. Agranular parts of the PFC emerged in early mammals, and rodents, primates, and other modern mammals share them by inheritance. These are limbic areas and include the agranular orbital cortex and agranular medial frontal cortex (areas 24, 32, and 25).
Todd M, Preuss, Steven P, Wise
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2010
The prefrontal cortex (PFC) circuits are characterized by several distinct features. First, the input–output connections of a PFC circuit with the rest of the brain are extraordinarily extensive. In the primates, pyramidal neurons in PFC are greatly more spinous than in the primary sensory areas, so they have a much larger capacity for synaptic ...
R. Hamish McAllister-Williams +199 more
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The prefrontal cortex (PFC) circuits are characterized by several distinct features. First, the input–output connections of a PFC circuit with the rest of the brain are extraordinarily extensive. In the primates, pyramidal neurons in PFC are greatly more spinous than in the primary sensory areas, so they have a much larger capacity for synaptic ...
R. Hamish McAllister-Williams +199 more
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Prefrontal cortex and depression
Neuropsychopharmacology, 2021The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in major depressive disorder (MDD). Although functional and structural PFC abnormalities have been reported in both individuals with current MDD as well as those at increased vulnerability to MDD, this information has not translated into better treatment and ...
Diego A. Pizzagalli, Angela C. Roberts
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2021
Abstract The key to the granular prefrontal (PF) cortex is that it sits at the top of the sensory processing hierarchy, the motor hierarchy, and the outcome hierarchy. This means that it is a position to learn abstract task rules. These relate to conditional tasks that involve sequences, associations, and attentional performance. Because
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Abstract The key to the granular prefrontal (PF) cortex is that it sits at the top of the sensory processing hierarchy, the motor hierarchy, and the outcome hierarchy. This means that it is a position to learn abstract task rules. These relate to conditional tasks that involve sequences, associations, and attentional performance. Because
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2021
Abstract In primates, the medial prefrontal cortex (PF) supports sequences of self-generated actions that are performed spontaneously and without external cues to instruct the action that is appropriate. Instead, the actions are performed on the basis of memories of previous events and their outcomes.
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Abstract In primates, the medial prefrontal cortex (PF) supports sequences of self-generated actions that are performed spontaneously and without external cues to instruct the action that is appropriate. Instead, the actions are performed on the basis of memories of previous events and their outcomes.
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