Results 1 to 10 of about 586 (172)
THIN-LAYER CHROMATOGRAPHY OF SOME PREGNENES AND PREGNADIENES
Journal of General and Applied Microbiology, 1974 The resolution of different steroids on a thin-layer plate with a large number of solvent systems was investigated. These steroids are of the pregnene models differing in the number and position of the double bond, and ketone and hydroxyl groups. The mobility of these steroids on the plate with the most suitable solvent systems (9 different systems ...
Lotfy A. Sallam +2 more
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Crystal data (I) for some pregnenes and pregnadienes [PDF]
Acta Crystallographica, 1964 B. A. Haner, D. A. Norton
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Synthesis and characterization of new aromatic esters based on 4,16-pregnadiene-6,20-dione skeleton [PDF]
Chemistry Central Journal, 2010 A series of new aromatic esters based on 4,16-pregnadiene-6,20-dione skeleton, namely 3β-benzoyloxy-4,16-pregnadiene-6,20-dione and 3β-furoyloxy-4,16-pregnadiene- 6,20-dione, which may be good inhibitors for the 5α-reductase enzyme and show high antiandrogenic activity, were synthesized starting from diosgenin.
Juan Li, Hongqi Li, Yijing Li
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Amino-derivatives of 11β,17α,21-Trihydroxy-3,20-Dioxo-1,4-Pregnadiene [PDF]
Nature, 1961 THE skeleton of corticosteroids was systematically modified, mainly in order to study the changes in the pharmacological effect of the compounds.
James L. Toth, Z. Tuba, L Szporny
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Crystal Structure and Synthesis of 3.BETA.-Acetoxy-4,16-pregnadiene-6,20-dione
Analytical Sciences: X-ray Structure Analysis Online, 2004 C23H30O4 is orthorhombic, P212121. The unit-cell dimensions at 293 K are a = 6.0490(3), b = 12.7788(7), c = 26.8859(15)A, V = 2078.25(19)A3, Dx = 1.184 g/cm3, and Z = 4. The R value is R = 0.050 for 3663 reflections. The A, B, C and D rings occur in distorted half chair, distorted chair, distorted chair, and distorted envelope conformations.
M. Soriano-Garcı́a +5 more
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Chemical and Pharmaceutical Bulletin, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Marisa Cabeza +6 more
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Crystal Structure and Synthesis of .BETA.-(p-Fluorobenzoyloxy)-4,16- pregnadiene-6,20-dione
Analytical Sciences: X-ray Structure Analysis Online, 2003 C28H31FO4 is monoclinic, P21. The unit-cell dimensions at 293 K are a = 12.4629(10), b = 6.1705(5), c = 15.5815(13)A, β = 102.243(2)°, V = 1171.00(17)A3, Dx = 1.278 g/cm3 and Z = 2. The R value is R = 0.048 for 4105 reflections. The A, B, C and D rings occur in half chair, distorted chair, distorted chair, and distorted envelope conformations.
M. Soriano-Garcı́a +5 more
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Chemical and Pharmaceutical Bulletin, 1974 Ten metabolites of 17α-acetoxy-6-chloro-4, 6-pregnadiene-3, 20-dione were isolated from urine and bile of the rabbit and their chemical structures were determined. The urinary main metabolite was 17α-acetoxy-2ξ, 3ξ-dihydroxy-5ξ-pregnan-20-one. The biliary main metabolite was 17α-acetoxy-6-chloro-2ξ, 3ξ-dihydroxy-4, 6-pregnadien-20-one. The administered
Tatsuya Abe, Akira Kambegawa
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Experimental Biology and Medicine, 1956 Summary(1) Meticorten and Meticortelone, 2 new steroids, were studied in animals to assess their adrenocortical activities. (2) Glucocorticoid properties were assayed by the eosinophil response in adrenalectomized mice, by the liver glycogen deposition in adrenalectomized rats, and by the involution of the thymus in immature rats. (3) By all 3 methods,
Sibylle Tolksdorf +5 more
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Synthesis of 20α- and 20β-Amino-3, 5-pregnadiene Derivatives and Antimicrobial Activity
Agricultural and Biological Chemistry, 1970 Y. NAGAI, Yuichiro Kurosawa
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