Results 1 to 10 of about 598 (175)
THIN-LAYER CHROMATOGRAPHY OF SOME PREGNENES AND PREGNADIENES
The resolution of different steroids on a thin-layer plate with a large number of solvent systems was investigated. These steroids are of the pregnene models differing in the number and position of the double bond, and ketone and hydroxyl groups. The mobility of these steroids on the plate with the most suitable solvent systems (9 different systems ...
Lotfy A. Sallam +2 more
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Crystal data (I) for some pregnenes and pregnadienes [PDF]
B. A. Haner, D. A. Norton
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New Polyhydroxylated Pregnadienes from the South African Soft Coral Pieterfaurea unilobata [PDF]
Seven pregnadiene metabolites, pregna-5,20-diene-3α,7α-diol 3α-acetate (1), pregna-5,20-diene-3β,7α-diol 7α-acetate (2), pregna-5,20-dien-3β-ol (3), pregna-5,20-diene-3α,7α,11α-triol 3α-acetate (4), pregna-5,20-diene-3α,7α, 11α-triol 3α,7α-diacetate (5), pregna-5,20-diene-3α,7α,19-triol 30, 19-diacetate (6), and pregna-5,20-diene-3α,7α,11α,19-tetrol 3α,
Denzil R. Beukes +4 more
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AbstractAus dem Cyclosteroid (I) sowie aus seinen Umlagerungsprodukten,den A‐Nor‐Steroid‐dienen (II) und (III), die in von der Reaktionsdauer abhängigen Ausbb.
E.‐J. BRUNKE +3 more
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ChemInform Abstract: SELECTIVE DOUBLE BOND ISOMERIZATIONS OF A-NOR-PREGNADIENES
AbstractDie Reaktionsfolge (IVa) ‐+ (Va)‐(VI)‐(VIII) wurde als Modelluntersuchung für die Totalsynthese des Pregnenons (VIII) durchgeführt.
BRUNKE
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Synthesis and characterization of new aromatic esters based on 4,16-pregnadiene-6,20-dione skeleton [PDF]
A series of new aromatic esters based on 4,16-pregnadiene-6,20-dione skeleton, namely 3β-benzoyloxy-4,16-pregnadiene-6,20-dione and 3β-furoyloxy-4,16-pregnadiene- 6,20-dione, which may be good inhibitors for the 5α-reductase enzyme and show high antiandrogenic activity, were synthesized starting from diosgenin.
Juan Li, Hongqi Li, Yijing Li
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Amino-derivatives of 11β,17α,21-Trihydroxy-3,20-Dioxo-1,4-Pregnadiene [PDF]
THE skeleton of corticosteroids was systematically modified, mainly in order to study the changes in the pharmacological effect of the compounds.
James L. Toth, Z. Tuba, L Szporny
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Crystal Structure and Synthesis of 3.BETA.-Acetoxy-4,16-pregnadiene-6,20-dione
C23H30O4 is orthorhombic, P212121. The unit-cell dimensions at 293 K are a = 6.0490(3), b = 12.7788(7), c = 26.8859(15)A, V = 2078.25(19)A3, Dx = 1.184 g/cm3, and Z = 4. The R value is R = 0.050 for 3663 reflections. The A, B, C and D rings occur in distorted half chair, distorted chair, distorted chair, and distorted envelope conformations.
M. Soriano-Garcı́a +5 more
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Crystal Structure and Synthesis of .BETA.-(p-Fluorobenzoyloxy)-4,16- pregnadiene-6,20-dione
C28H31FO4 is monoclinic, P21. The unit-cell dimensions at 293 K are a = 12.4629(10), b = 6.1705(5), c = 15.5815(13)A, β = 102.243(2)°, V = 1171.00(17)A3, Dx = 1.278 g/cm3 and Z = 2. The R value is R = 0.048 for 4105 reflections. The A, B, C and D rings occur in half chair, distorted chair, distorted chair, and distorted envelope conformations.
M. Soriano-Garcı́a +5 more
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Notes- Stereospecific Microbiological Reduction of 3-Ket-1,4-pregnadienes to 3-Keto-1-pregnenes.
G. Greenspan +4 more
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