Results 31 to 40 of about 598 (175)
Biosynthesis of 3β‐hydroxy‐5,7‐pregnadien‐20‐one by the horse fetal gonad
The production of equilin and the other ring B‐unsaturated estrogens by the pregnant mare is anomalous in that they are biosynthesised by a cholesterol‐independent pathway. Fetal horse gonads were incubated with tritiated sodium acetate and radiochemically pure 3β‐hydroxy‐5,7‐pregnadien‐20‐one and 3β‐hydroxy‐5,7‐androstadien‐17‐one were isolated.
Tait, A.D., Hodge, L.C., Allen, W.R.
openaire +2 more sources
The Mycobacterium tuberculosis (Mtb) igr operon plays an essential role in Mtb cholesterol metabolism, which is critical for pathogenesis during the latent stage of Mtb infection.
Meng Yang +4 more
semanticscholar +1 more source
Understanding the molecular pathways perturbed in smokeless tobacco- (ST) associated head and neck squamous cell carcinoma (HNSCC) is critical for identifying novel complementary agents for effective disease management.
M. Macha +4 more
semanticscholar +1 more source
We have identified the MSMEG_6561 gene, encoding an aldolase responsible for the transformation of 22‐hydroxy‐3‐oxo‐cholest‐4‐ene‐24‐carboxyl‐CoA (22‐OH‐BCN‐CoA) into the 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) precursor (20S)‐3‐oxopregn‐4‐ene‐20‐carboxaldehyde (3‐OPA).
Gabriel Hernández‐Fernández +3 more
wiley +1 more source
Cholesterol catabolism plays an important role in Mycobacterium tuberculosis's (Mtb's) survival and persistence in the host. Mtb exploits three β-oxidation cycles to fully degrade the side-chain of cholesterol.
Tianao Yuan +3 more
semanticscholar +1 more source
Structural and synthetic investigations of South African marine natural products [PDF]
A chemical investigation of six different marine invertebrates, collected along the South African coastline, resulted in the isolation and structural elucidation of fifteen previously undescribed secondary metabolites along with seven known compounds ...
Beukes, Denzil Ronwynne
core +1 more source
Sinteza novih derivata testosterona sa supstituiranim pirazolinskim prstenom kao inhibitori 5alpha-reduktaze [PDF]
Condensation of 3β-hydroxy-16-[(4-chlorophenyl)methylene]androst-5-en-17-one 1 with hydrazine hydrate in acetic acid afforded N-acetyl pyrazoline derivative 2, while, condensation of 1 with semicarbazide afforded compound 3.
ABD EL-GALIL EL-SAYED AMR +2 more
core +1 more source
Glucocorticoids (GCs) have been used for decades in the treatment of chronic inflammatory and autoimmune diseases, thanks to their powerful anti‐inflammatory properties.
Joanny, Marie‐Eugénie
core +1 more source
Estudo físico-químico dos polimorfos da progesterona e estabilização da forma metaestável sobre matrizes poliméricas [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaA nucleação heterogênea induzida por polímeros (PIHn) é uma técnica inovadora utilizada no "screening" de polimorfos na ...
Sibaja, Andrea Mariela Araya
core
Role of macrophage 11β-HSD1 in inflammation mediated angiogenesis, arthritis and obesity [PDF]
11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1, encoded by Hsd11b1) is an enzyme that predominantly converts inactive glucocorticoids (cortisone in human and most mammals, 11dehydro-corticosterone in mice and rats) into their active forms (cortisol
Zhang, Zhenguang
core

