Results 51 to 60 of about 314,865 (313)

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

Advanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier, Justin Christopher D'Antin, Gemma Julio, Anna Roig   +3 more
wiley   +1 more source

Loss of Endometrial Plasticity in Recurrent Pregnancy Loss [PDF]

Stem Cells, 2015
Abstract Menstruation drives cyclic activation of endometrial progenitor cells, tissue regeneration, and maturation of stromal cells, which differentiate into specialized decidual cells prior to and during pregnancy. Aberrant responsiveness of human endometrial stromal cells (HESCs) to deciduogenic cues is strongly associated with ...
Lucas, ES, Dyer, NP, Murakami, K, Hou Lee, Y, Chan, YW, Grimaldi, G, Muter, J, Brighton, PJ, Moore, JD, Patel, G, Chan, JKY, Takeda, S, Lam, EWF, Quenby, S, Ott, S, Brosens, JJ   +15 more
openaire   +6 more sources

Smart Sampling Capsule for Capture and Detection of Enteric Pathogens in the Small Intestine

Advanced Materials Technologies, EarlyView.
An ingestible smart sampling capsule for capturing asymptomatic enteric pathogens at their primary sites of interaction within the small intestine. This capability enables non‐invasive detection of early pathogen colonization within the gut environment prior to fecal shedding, providing a robust approach for pathogen surveillance and microbiome studies.
Akshay Krishnakumar, Devendra Sarnaik, Nicholas L. F. Gallina, Robyn R. McCain, Christa Crain, Arun K. Bhunia, Rahim Rahimi   +6 more
wiley   +1 more source

Bridging the gap between pregnancy loss research and policy and practice: insights from a qualitative survey with knowledge users

Health Research Policy and Systems
Background The loss of a pregnancy or the death of baby around the time of their birth can have profound impacts on parents, families and staff involved.
Marita Hennessy, Keelin O’Donoghue
doaj   +1 more source

Pregnancy Loss and Cancer Risk: A Nationwide Observational Study

EClinicalMedicine, 2019
Background: Cancer is the second leading cause of death worldwide. Few studies have investigated if recurrent pregnancy loss is associated with an increased risk of cancer.
Anders P. Mikkelsen, Pia Egerup, Julie F.M. Ebert, Astrid M. Kolte, Henriette S. Nielsen, Øjvind Lidegaard   +5 more
doaj   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions

Reproductive Biology and Endocrinology, 2018
Recurrent implantation failure (RIF) refers to cases in which women have had three failed in vitro fertilization (IVF) attempts with good quality embryos. The definition should also take advanced maternal age and embryo stage into consideration.
Asher Bashiri, Katherine Ida Halper, Raoul Orvieto   +2 more
doaj   +1 more source

Assessment of In Vitro and In Silico Protocols for Sequence-Based Characterization of the Human Vaginal Microbiome

mSphere, 2020
The vaginal microbiome has been connected to a wide range of health outcomes. This has led to a thriving research environment but also to the use of conflicting methodologies to study its microbial composition.
Luisa W. Hugerth, Marcela Pereira, Yinghua Zha, Maike Seifert, Vilde Kaldhusdal, Fredrik Boulund, Maria C. Krog, Zahra Bashir, Marica Hamsten, Emma Fransson, Henriette Svarre Nielsen, Ina Schuppe-Koistinen, Lars Engstrand   +12 more
doaj   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Advanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Yuting Guan, Virginia Man‐Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu   +14 more
wiley   +1 more source