Results 201 to 210 of about 235,181 (316)

The phenolic complex in flaxseed [PDF]

, 2008
Flaxseed is the richest plant source of the lignan secoisolariciresinol diglucoside (SDG). In flaxseed, SDG exists in an oligomeric structure with 3-hydroxy-3-methyl glutaric acid (HMGA) forming a phenolic complex together with p-coumaric acid and ...
Strandås, Christina
core  

Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway. [PDF]

CNS Neurosci Ther, 2023
Xuan LN, Hu ZX, Jiang ZF, Zhang C, Sun XW, Ming WH, Liu HT, Qiao RF, Shen LJ, Liu SB, Wang GY, Wen L, Luan ZL, Yin J.   +13 more
europepmc   +1 more source

The Mycoestrogen Zearalenone Induces CYP3A through Activation of the Pregnane X Receptor [PDF]

, 2006
Xunshan Ding, Kristin Lichti, Jeff L. Staudinger   +2 more
openalex   +1 more source

Photochemotherapeutic Agent 8-Methoxypsoralen Induces Cytochrome P450 3A4 and Carboxylesterase HCE2: Evidence on an Involvement of the Pregnane X Receptor [PDF]

, 2006
Jian Yang, Bingfang Yan
openalex   +1 more source

Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system

Stem Cell Research, 2018
Pregnane X receptor (PXR) is a key nuclear receptor that mediates drug metabolism and stimulates hepatocyte proliferation. However, the lack of PXR expression in human pluripotent stem cell-derived hepatocytes limits their application for drug screening ...
Hyemin Kim, Ji-Woo Kim, So-Jin Kim, Young-Jun Choi, Dae-Sung Kim, Han-Jin Park   +5 more
doaj  

Lipopolysaccharide and Cecal Ligation/Puncture Differentially Affect the Subcellular Distribution of the Pregnane X Receptor but Consistently Cause Suppression of Its Target Genes CYP3A

, 2003
Karuna Sachdeva, Bingfang Yan, Clinton O. Chichester   +2 more
openalex   +1 more source

Lack of association of the pregnane X receptor (PXR/NR1I2) gene with inflammatory bowel disease: parallel allelic association study and gene wide haplotype analysis [PDF]

, 2006
Gwo–Tzer Ho, Nicole Soranzo, Sarah K. Tate, Hazel E. Drummond, Elaine R. Nimmo, Albert Tenesa, Ian Arnott, Jack Satsangi   +7 more
openalex   +1 more source

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers [PDF]

, 2006
Stephanie Faucette, Tong-Cun Zhang, Rick Moore, Tatsuya Sueyoshi, Curtis J. Omiecinski, Edward L. LeCluyse, Masahiko Negishi, Hongbing Wang   +7 more
openalex   +1 more source

Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling. [PDF]

Acta Pharmacol Sin, 2023
Ming WH, Luan ZL, Yao Y, Liu HC, Hu SY, Du CX, Zhang C, Zhao YH, Huang YZ, Sun XW, Qiao RF, Xu H, Guan YF, Zhang XY.   +13 more
europepmc   +1 more source

Pregnane X Receptor Activators Inhibit Human Hepatic Stellate Cell Transdifferentiation In Vitro [PDF]

, 2006
Emma Louise Haughton, Steven Tucker, Carylyn J. Marek, Elaine Durward, Val Leel, Zainab Bascal, Tanya Monaghan, Matthew Koruth, Elaina Collie‐Duguid, Derek A. Mann, Julie E. Trim, Matthew C. Wright   +11 more
openalex   +1 more source