Results 1 to 10 of about 146,907 (264)

Steroid receptors in meningiomas [PDF]

Arquivos de Neuro-Psiquiatria, 1985
Cytosolic estrogen (ER), progesterone (PR), androgen (AR) and glucocorticoid receptors (GR) were evaluated in 10 meningiomas using a dextran charcoal coated method. We consider as positive specific receptor values >10fMol/mg protein. In this study 20% of
J. P. P. Plese, V. R. Martins, M. T. P. Lopes, M. M. Brentani   +3 more
doaj   +4 more sources

Steroid hormone receptors: an update [PDF]

Human Reproduction Update, 2000
Steroid hormones (SHs) are lipophilic molecules derived from cholesterol and synthesized in the adrenal cortex (glucocorticoids, mineralocorticoids, and adrenal androgens), the testes (testicular androgens, oestrogen), and the ovary and placenta (oestrogens and progestagens or progestins).
MIGUEL Beato, J Klug
exaly   +3 more sources

Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors. [PDF]

PLoS ONE, 2010
BackgroundTetratricopeptide repeat (TPR) motif containing co-chaperones of the chaperone Hsp90 are considered control modules that govern activity and specificity of this central folding platform. Steroid receptors are paradigm clients of Hsp90.
Jan-Philip Schülke, Gabriela Monika Wochnik, Isabelle Lang-Rollin, Nils Christian Gassen, Regina Theresia Knapp, Barbara Berning, Alexander Yassouridis, Theo Rein   +7 more
doaj   +1 more source

Importins involved in the nuclear transportation of steroid hormone receptors: In silico and in vitro data

Frontiers in Endocrinology, 2022
The nuclear receptor superfamily (NRS) consists of 48 receptors for lipophilic substances and is divided into 7 different subfamilies, with subfamily 3 comprising steroid hormone receptors.
Konstantina Kalyvianaki, Athanasios A. Panagiotopoulos, Maria Patentalaki, Elias Castanas, Marilena Kampa   +4 more
doaj   +1 more source

Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids

Genes and Environment, 2020
Background Sex steroid hormone receptors are classified into three classes of receptors: estrogen receptors (ER) α and β, androgen receptor (AR), and progesterone receptor (PR).
Sayoko Ito-Harashima, Mami Matano, Kana Onishi, Tomofumi Nomura, Saki Nakajima, Shingo Ebata, Kazuhiro Shiizaki, Masanobu Kawanishi, Takashi Yagi   +8 more
doaj   +1 more source

G protein-coupled receptors function as cell membrane receptors for the steroid hormone 20-hydroxyecdysone

Cell Communication and Signaling, 2020
G protein-coupled receptors (GPCRs) are cell membrane receptors for various ligands. Recent studies have suggested that GPCRs transmit animal steroid hormone signals.
Xiao-Fan Zhao
doaj   +1 more source

Modulatory Effects of Sex Steroids Progesterone and Estradiol on Odorant Evoked Responses in Olfactory Receptor Neurons. [PDF]

PLoS ONE, 2016
The influence of the sex steroid hormones progesterone and estradiol on physiology and behavior during menstrual cycles and pregnancy is well known. Several studies indicate that olfactory performance changes with cyclically fluctuating steroid hormone ...
Ninthujah Kanageswaran, Maximilian Nagel, Paul Scholz, Julia Mohrhardt, Günter Gisselmann, Hanns Hatt   +5 more
doaj   +1 more source

Modulation of Xenobiotic Receptors by Steroids

Molecules, 2013
Nuclear receptors (NRs) are ligand-activated transcription factors that regulate the expression of their target genes. NRs play important roles in many human diseases, including metabolic diseases and cancer, and are therefore a key class of therapeutic ...
Delira Robbins, Monimoy Banerjee, Taosheng Chen   +2 more
doaj   +1 more source

Coumarins as Tool Compounds to Aid the Discovery of Selective Function Modulators of Steroid Hormone Binding Proteins

Molecules, 2021
Steroid hormones play an essential role in a wide variety of actions in the body, such as in metabolism, inflammation, initiating and maintaining sexual differentiation and reproduction, immune functions, and stress response.
Sanna Niinivehmas, Olli T. Pentikäinen
doaj   +1 more source

The roles of sex steroid receptor coregulators in cancer

Molecular Cancer, 2002
Sex steroid hormones, estrogen, progesterone and androgen, play pivotal roles in sex differentiation and development, and in reproductive functions and sexual behavior.
Loggie Brian W, Gao Xiuhua, Nawaz Zafar
doaj   +1 more source