Results 31 to 40 of about 798,182 (300)

Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA.

PLoS ONE, 2014
The steroid hormone receptors regulate important physiological functions such as reproduction, metabolism, immunity, and electrolyte balance. Mutations within steroid receptors result in endocrine disorders and can often drive cancer formation and ...
William H Hudson, Christine Youn, Eric A Ortlund   +2 more
doaj   +1 more source

Differential Expression of Steroid Hormone Receptors and Ten Eleven Translocation Proteins in Endometrial Cancer Cells

Frontiers in Oncology, 2022
Steroid hormones govern the complex, cyclic changes of the endometrium, predominantly through their receptors. An interplay between steroid hormones and epigenetic mechanisms controls the dynamic endometrial gene regulation.
Vishakha Mahajan, Palak Gujral, Palak Gujral, Lekha Jain, Lekha Jain, Anna P. Ponnampalam, Anna P. Ponnampalam, Anna P. Ponnampalam   +7 more
doaj   +1 more source

A Review on Sex Steroid Hormone Estrogen Receptors in Mammals and Fish

International Journal of Endocrinology, 2020
Steroid hormones play essential roles in the reproductive biology of vertebrates. Estrogen exercises its effect through estrogen receptors and is not only a female reproductive hormone but acts virtually in all vertebrates, including fish, and is ...
Eric Amenyogbe, Gang Chen, Zhongliang Wang, Xiaoying Lu, Mingde Lin, Ai Ying Lin   +5 more
doaj   +1 more source

Androgen-induced migration in NIH3T3 mouse fibroblasts: role of AR association with Filamin A. [PDF]

, 2010
Androgen stimulation triggers rapid activation of various signaling effectors in target cells (Migliaccio et al. 2000; Castoria et al. 2003). This occurs through a direct interaction of classical steroid receptors with proto-oncogenic tyrosine kinase ...
Giraldi, Tiziana
core   +1 more source

Prostate cancer and therapeutic challenges

Journal of Biological Research - Thessaloniki, 2020
Prostate cancer (PC) is the most prevalent type of cancer in men worldwide. In Saudi Arabia, the rate of PC is increasing annually. The sex steroid hormones androgens and their receptors have critical roles in PC development and progression. Additionally,
Yousef MohammedRabaa Hawsawi, Samar Abdullah Zailaie, Atif Abdulwahab A. Oyouni, Othman Rashed Alzahrani, Osama Mohamed Alamer, Saad Ali S. Aljohani   +5 more
doaj   +1 more source

The reciprocal regulation of stress hormones and GABAA receptors

Frontiers in Cellular Neuroscience, 2012
Stress-derived steroid hormones regulate the expression and function of GABAA receptors (GABAARs). Changes in GABAAR subunit expression have been demonstrated under conditions of altered steroid hormone levels, such as stress, as well as following ...
Istvan eMody, Jamie eMaguire
doaj   +1 more source

Evidence for a GABAergic system in rodent and human testis: Local GABA production and GABA receptors [PDF]

, 2003
The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors.
Doepner, Richard F. G., Frungieri, Monica Beatriz, Kohn, Frank M., Doepner, R., Gamel-Didelon, Katia, Geigerseder, C., Mayerhofer, Artur, Thalhammer, A,, Geigerseder, Christof, Frungieri, Monica B., Köh, F. M., Calandra, Ricardo Saul, Calandra, Ricardo S., Gamel Didelon, K., Thalhammer, Andrea, Geigerseder, Christof;Doepner, Richard;Thalhammer, Andrea;Frungieri, Monica B.;Gamel-Didelon, Katia;Calandra, Ricardo S.;Köhn, Frank M.;Mayerhofer, Artur, Geigerseder, C;Doepner, R;Thalhammer, A;Frungieri, MB;Gamel-Didelon, K;Calandra, RS;Köhn, FM;Mayerhofer, A   +16 more
core   +1 more source

Cortisol synthesis by primary human keratinocytes [PDF]

, 2009
PhDCortisol analogues have been used to treat skin disorders, such as psoriasis and atopic dermatitis, for over 50 years but the ability of normal human keratinocytes to synthesise cortisol has not been reported.
Hannen, Rosalind Francesca
core   +4 more sources

The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers

International Journal of Endocrinology, 2013
The “endocannabinoid system (ECS)” comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport ...
Thangesweran Ayakannu, Anthony H. Taylor, Timothy H. Marczylo, Jonathon M. Willets, Justin C. Konje   +4 more
doaj   +1 more source

3D model of amphioxus steroid receptor complexed with estradiol [PDF]

, 2009
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
Michael E. Baker, David J. Chang
core