Results 181 to 190 of about 2,109,783 (360)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Lactation Practices in Critically Ill PatientsTake-Home Points
Background: Most birthing people in the United States initiate lactation, but little is known about lactation practices in patients who are critically ill.
Kayla J. Kolbe, MD +7 more
doaj +1 more source
Prepped for Success? Supporting Pregnant and Parenting Teens in Chicago Schools [PDF]
In 2000, there were 8,153 births to mothers under the age of 20 in the city of Chicago. Forty-one percent of those births (3321) were to teenagers 17 or younger.
Helene M. Marcy
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Prevalence of obesity in pregnant women referred to health centers Ardabil 1388 [PDF]
The prevalence of obesity in recent years and especially in developing countries, has increased dramatically. It is important for obesity that can cause heart disease, diabetes, high blood pressure, abnormalities of Obstetrics and Gynecology and many ...
اسدزاده, فيروزه +5 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Factor Influencing Gender Based Violence Among Pregnant Women Attending Antenatal Clinic in PHC of Syangja District, Nepal [PDF]
Pregnancy and childbirth were a time of unique vulnerability to violence victimization because of changes in women’s physical, social, emotional, and economic needs during pregnancy.
Acharya, J. (Jeevan) +1 more
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

