Simultaneous genome-wide haplotyping and copy number detection enables universal equine preimplantation genetic testing [PDF]
, 2023 Tine De Coster +6 more
openalex +1 more source
Attitudes Towards and Prevalence of Son Preference and Sex Selection in South Asian American Communities in the United States [PDF]
, 2012 This report summarizes research conducted by Generations Ahead, a social justice non-profit in the United States, within the South Asian American community.
Sujatha Jesudason
core
Artificial Organs, EarlyView.Multicenter real‐world cohort (n = 327) comparing LVADs: HeartMate 3 (HM3), HeartMate II (HMII), and HeartWare (HVAD). HM3 showed superior long‐term survival versus legacy devices, driven by fewer hemocompatibility‐related adverse events, especially pump thrombosis and ischemic stroke, while major bleeding was similar across devices.
Hamza H. H. Ben Nasir +9 more
wiley +1 more source
Cell Proliferation, EarlyView.Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source
Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos
Cell Proliferation, EarlyView.Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang +10 more
wiley +1 more source
Selección de sexo en fase embrionaria: una visión desde la ciencia, la ética y el derecho [PDF]
, 2017 La opción de elegir el sexo de la descendencia es un deseo mostrado desde la antigüedad por múltiples culturas. Los métodos propuestos han sido diversos, todos ellos discutibles ya que carecían de evidencia científica o suponían el aborto y un ...
Jiménez González, Joaquín
core +1 more source
Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss
Equine Veterinary Journal, EarlyView.Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez +6 more
wiley +1 more source
Academia Molecular Biology and GenomicsConventional preimplantation genetic testing for aneuploidy (PGT-A) and for monogenic disorders (PGT-M) is very limited in scope. These methods typically assess chromosomal ploidy or target only one or two specific variants carried by the ...
Benjamin Podgursky +12 more
doaj +1 more source
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Effects of Gender of Reciprocal Chromosomal Translocation on Blastocyst Formation and Pregnancy Outcome in Preimplantation Genetic Testing [PDF]
, 2021 Hui Song +6 more
openalex +1 more source