Results 51 to 60 of about 16,266,038 (328)

Design of a Low-Cost Easy-to-Fly STOL Ultralight Aircraft in Composite Material

Acta Polytechnica, 2005
The paper deals with the design of an aircraft, starting from a market survey, the conceptual design loop and the preliminary choice of dimensions, and leading to the detailed design of efficient high-lift systems and a low-drag fuselage shape ...
D. P. Coiro, A. de Marco, F. Nicolosi, N. Genito, S. Figliolia   +4 more
doaj  

Determination of Regression Formulas for Key Design Characteristics of Container Ships at Preliminary Design Stage

New Trends in Production Engineering, 2018
This article presents regression equations to estimate container ship design characteristics based on the most up-to-date data and deadweight capacity, the number of containers and their combination at the preliminary design stage.
T. Abramowski, T. Cepowski, P. Zvolenský   +2 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

New Trends Towards Enhanced Structural Efficiency and Aesthetic Potential in Tall Buildings: The Case of Diagrids

Applied Sciences, 2020
Due to the increasing number of people and activities within the cities, tall buildings are exploited worldwide to address the need for new living and commercial spaces, while limiting the amount of used land.
Domenico Scaramozzino, Giuseppe Lacidogna, Alberto Carpinteri   +2 more
doaj   +1 more source

Preliminary design of a medium‐power modular lead‐cooled fast reactor with the application of optimization methods

International Journal of Energy Research, 2018
Based on research and development experience from Gen III, Gen III+, and Gen IV reactor concepts, a 1000‐MWt medium‐power modular lead‐cooled fast reactor M2LFR‐1000 was developed by University of Science and Technology of China (USTC), aiming at ...
Hongli Chen, Xilin Zhang, Y. Zhao, Liankai Cao, Kangli Shi, Fang Haitao, Chong Shen, H. Zhang, Q. Zeng   +8 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

RoomDreaming: Generative-AI Approach to Facilitating Iterative, Preliminary Interior Design Exploration

International Conference on Human Factors in Computing Systems
Interior design aims to create aesthetically pleasing and functional environments within an architectural space. For a simple room, the preliminary design exploration currently takes multiple meetings and days of work for interior designers to ...
Shun-Yu Wang, Wei Su, Serena Chen, Ching-Yi Tsai, Marta Misztal, Katherine M. Cheng, Alwena Lin, Yu Chen, Mike Y. Chen   +8 more
semanticscholar   +1 more source

Preliminary design and optimization of toroidally-wound limited angle servo motor based on a generalized magnetic circuit model [PDF]

, 2016
This paper proposes a new generalized equivalent magnetic circuit model for the preliminary design of a toroidally-wound limited angle servo motor (LASM).
Jiao, Zongxia, Li, Xiao, Luk, Patrick Chi-Kwong, Wu, Shuai, Zhao, Xiangyu   +4 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Conceptual Advanced Transport Aircraft Design Configuration for Sustained Hypersonic Flight

Aerospace, 2018
The conceptual aircraft design and its integration with a combined cycle engine for hypersonic cruise at Mach 8 is documented in this paper. The paper describes the process taken to develop a hypersonic aircraft from a conceptual approach. The discussion
Can Alkaya, Ashish Alex Sam, Apostolos Pesyridis   +2 more
doaj   +1 more source