Results 61 to 70 of about 883,299 (307)

Preliminary Design of Larch/C++

open access: yes, 1993
We describe the problems encountered in the design of Larch/C++, especially its object-oriented features. We discuss a range of possible solutions to these problems, and give the rationale for our particular solutions. We also present examples of Larch/C++ specifications and discuss differences from Larch/C.
Leavens, Gary, Cheon, Yoonsik
openaire   +3 more sources

Set-Based Design Method Reflecting the Different Designers’ Intentions [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThe previous series of the study have proposed a preference set-based design (PSD) method that enables the flexible and robust design under various sources of uncertainties. In contrast to the traditional design method,
Ishikawa, H., Inoue, M.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Simply Curved Shear Panel Theory in Three-Dimensional Space

open access: yesAerospace
The increasing complexity of large-scale thin-walled structures can be effectively addressed using hierarchical modelling approaches. However, in structural engineering, true preliminary design phases are often skipped due to the unavailability or ...
Moritz Bäß, Kai-Uwe Schröder
doaj   +1 more source

The preliminary successes and drawbacks of a turn to distance design studio learning.

open access: yes, 2020
It seems the technological campuses of tomorrow have manifested today as an essential and spontaneous response to the COVID-19 world outbreak. This article briefly discusses the current pivot from an on-campus physical design studio curriculum towards a ...
Marshalsey, Lorraine
core  

Work Roll Cooling System Design Optimisation in Presence of Uncertainty [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThe paper presents a framework to optimise the design of work roll based on the cooling performance. The framework develops Meta models from a set of Finite Element Analysis (FEA) of the roll cooling.
Onisa, C.   +5 more
core  

Preliminary design of the COMPASS upgrade tokamak

open access: yes, 2021
COMPASS Upgrade is a new medium size, high magnetic field tokamak (R = 0.9 m, Bt = 5 T, Ip = 2 MA) currently under design in the Czech Republic. It will provide unique capabilities for addressing some of the key challenges in plasma exhaust physics ...
Weinzettl, Vladimír   +96 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Preferences-based approach for TRIZ contradiction matrix exploitation in preliminary design [PDF]

open access: yesFME Transactions, 2020
The TRIZ theory has demonstrated its effectiveness in solving creative problems in the product design field. However, its exploitation and the application of its various tools and techniques remain difficult for the nonexperts. Generally, the theory does
Hmina Khadija   +3 more
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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