Results 81 to 90 of about 883,299 (307)

Preliminary design of multiple gravity-assist trajectories

open access: yes, 2006
In this paper the preliminary design of multiple gravity-assist trajectories is formulated as a global optimization problem. An analysis of the structure of the solution space reveals a strong multimodality, which is strictly dependent on the complexity ...
Vasile, Massimiliano   +2 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Investigating the geometry and control surface of AUV robots on hydrodynamics performance

open access: yesنشریه مهندسی دریا, 2021
Underwater equipment is a set of marine equipment used for purposes such as exploration, drilling, submarine cabling, maintenance and repair of offshore structures, and military applications.
Mohammad Saeed Seif, Ali Hasanvand
doaj  

Preliminary Design of Indonesian Military Surveilance Satellite

open access: yes, 2016
Considering the fast area of Indonesia, its military will need platform with high coverage such assatellite to ensure proper observation of its defense territory.
Hari Muhammad   +3 more
core  

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai   +5 more
wiley   +1 more source

Preliminary of User Interface Design for Picture Archiving and Communication System

open access: yes, 2013
[[abstract]]In order to gain entry to modern and technology, medical imaging technology not only has to economically storing, and conveniently accessing, images from multiple modalities, but also focus on user’s experience and interaction.
Lin, Wei-Chun Winine;Lee, Yuan-Zone
core  

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Open-Source Data Formalization through Model-Based Systems Engineering for Concurrent Preliminary Design of CubeSats

open access: yesAerospace
Market trends in the space sector suggest a notable increase in satellite operations and market value for the coming decade. In parallel, there has been a shift in the industrial and academic sectors from traditional Document-Based System Engineering to ...
Giacomo Luccisano   +3 more
doaj   +1 more source

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