Results 71 to 80 of about 883,299 (307)

On the Importance of Morphing Deformation Scheduling for Actuation Force and Energy

open access: yesAerospace, 2016
Morphing aircraft offer superior properties as compared to non-morphing aircraft. They can achieve this by adapting their shape depending on the requirements of various conflicting flight conditions.
Roeland De Breuker, Noud Werter
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Acquisition and sharing of innovative manufacturing knowledge for preliminary design [PDF]

open access: yes, 2009
This study investigates the identification, acquisition and sharing of innovative manufacturing knowledge for the preliminary design of complex mechanical components.
Mountney, Sara
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

An Approximate Method for Calculation of Mean Statistical Value of Ship Service Speed on a Given Shipping Line , Useful in Preliminary Design Stage

open access: yesPolish Maritime Research, 2015
During ship design, its service speed is one of the crucial parameters which decide on future economic effects. As sufficiently exact calculation methods applicable to preliminary design stage are lacking the so called contract speed which a ship reaches
Żelazny Katarzyna
doaj   +1 more source

ANALYSIS OF APPROACHES TO RISK MANAGEMENT IN PROJECTS OF DEVELOPING COMPLEX TECHNICAL PRODUCTS

open access: yesВісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2016
The importance of complex technical products and the role of design phase in developing these products are stated. Some specific features which indicate the high degree of uncertainty and risk in this phase (preliminary design of aviation engines as a ...
Али ЧЕНАРАНИ   +2 more
doaj   +1 more source

Design Rework Prediction in Concurrent Design Environment: Current Trends and Future Research Directions [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThis paper aims to present state-of-the-art and formulate future research areas on design rework in concurrent design environment. Related literatures are analysed to extract the key factors which impact design rework.
Shehab, Essam   +3 more
core  

Assessing, aggregating and visualising preliminary design information maturity to support collaborative design

open access: yes, 2020
Engineering projects involve the progressive development of preliminary information until a final design is reached. Appreciating its status may help make better decisions about task sequencing and may reduce unnecessary iteration. We present an approach
Brinkmann, Jens, Wynn, David
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Inovatyvaus šakotinio plieninio vantinio pėsčiųjų tilto lyginamoji analizė / Comparative analysis of innovative branched steel cable-stayed pedestrian bridge

open access: yesMokslas: Lietuvos Ateitis, 2018
Innovative steel cable-stayed pedestrian bridge design review is provided. The design advantages and disadvantages are presented. Innovative steel cable-stayed pedestrian bridge construction comparative analysis with similar 80 m span cable-stayed bridge
Modestas Stragys
doaj   +1 more source

Home - About - Disclaimer - Privacy