Results 51 to 60 of about 2,332,453 (308)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Practical Considerations Regarding the Preliminary Ruling Procedure Under Article 177 of the EEC Treaty [PDF]
, 1986 Part I of this Article considers the role played by the preliminary ruling procedure in the context of the Community legal system as a whole. Part II discusses the types of questions that may be appropriately referred to the Court for preliminary ruling.
Dauses, Manfred A.
core +2 more sources
A Compact Index for Order-Preserving Pattern Matching
, 2017 Order-preserving pattern matching was introduced recently but it has already attracted much attention. Given a reference sequence and a pattern, we want to locate all substrings of the reference sequence whose elements have the same relative order as the
Decaroli, Gianni +2 more
core +1 more source
Checklist of the Marine Fauna and Flora Reported from the Region of Aransas Pass, Texas [PDF]
, 1960 This checklist is of preliminary form with the hope that this will be a beginning for a more complete annotated list of the fauna and flora of this region. In many cases, this list is quite obviously incomplete, such as the algae, for which there are
Trott, Lamarr B.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
IASSIST Quarterly, 2016 Understanding Academic Patrons’ Data Needs through Virtual Reference Transcripts: Preliminary Findings from New York University ...
Margaret Smith +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Reference system characterization and cost overview [PDF]
, 1980 A brief description of the necessary elements of the Satellite Power System is presented.
Piland, R. O.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Rekayasa MesinThe need to develop ultra-micro gas turbine (TGUM) applications is getting higher, especially as a portable energy source. Many applications whose energy requirements cannot be met by current batteries but can be handled by TGUM.
Muhamad Maris Al Gifari +3 more
doaj +1 more source