Results 231 to 240 of about 80,493 (290)

Transcriptional and functional effects of mavacamten in multiple porcine and human models with hypertrophic cardiomyopathy

British Journal of Pharmacology, Volume 183, Issue 5, Page 1122-1139, March 2026.
Abstract Background and Purpose Mavacamten (MAVA) is a novel small molecule inhibitor of cardiac myosin, mitigating cardiomyocyte hypercontractility in patients with hypertrophic obstructive cardiomyopathy (HOCM). Despite its recent approval for clinical use, the transcriptional and functional impacts of MAVA remain not well understood.
Elisa Kiselev, Wilson Agyapong, Bjarne Jürgens, Elisa Mohr, Shambhabi Chatterjee, Hannah J. Hunkler, Jawad Salman, Giuseppe Cipriano, Marco Bentele, Junqing Liu, Jonas Specht, Kaja S. Menge, Florian J. G. Waleczek, Jonas A. Haas, Anselm A. Derda, Kristina Sonnenschein, Anika Gietz, Susanne Neumüller, Angelika Pfanne, Oliver Beetz, Michael Pflaum, Bettina Wiegmann, Yiangos Psaras, Christopher Toepfer, Robert Zweigerdt, Ante Radocaj, Theresia Kraft, Andre Zeug, Evgeni Ponimaskin, Wilhelm Korte, Alexander Horke, Arjang Ruhparwar, Maximilian Fuchs, Ke Xiao, Christian Bär, Natalie Weber, Thomas Thum   +36 more
wiley   +1 more source

Non-Invasive Hemodynamic Monitoring in Critically Ill Patients: A Guide for Emergency Physicians. [PDF]

J Clin Med
Beltrame M, Bellan M, Patrucco F, Gavelli F.   +3 more
europepmc   +1 more source

Sex differences in trial representation and the cardiovascular effectiveness of newer glucose‐lowering agents in patients with and without type 2 diabetes: A systematic review and meta‐analysis of cardiovascular outcome trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2183-2202, March 2026.
Abstract Aims The extent to which the cardiovascular benefits of sodium–glucose co‐transporter 2 inhibitors (SGLT‐2is) and glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) differ by sex remains unclear. This systematic meta‐analysis aimed to investigate sex differences in trial representation and the cardiovascular and kidney efficacy of SGLT‐2is ...
Magdaline Zawadka, Erwin Taguiam, Mê‐Linh Lê, Rohan Sanjanwala, Shuangbo Liu, Ashish H. Shah, Setor K. Kunutsor   +6 more
wiley   +1 more source

Influence of Digital Manufacturing and Abutment Design on Full-Arch Implant Prostheses-An In Vitro Study. [PDF]

Materials (Basel)
Altwaijri S, Alotaibi H, Alnassar TM, Aldegheishem A.   +3 more
europepmc   +1 more source

From microgravity to hypergravity: Perspectives on circulatory adaptation through multiscale modelling

The Journal of Physiology, EarlyView.
Dario Collia, Luigino Zovatto, Gianni Pedrizzetti   +2 more
wiley   +1 more source

Egg Adhesion of the Codling Moth Cydia pomonella L. (Lepidoptera, Tortricidae) to Synthetic Substrates

Journal of Applied Entomology, Volume 150, Issue 2, Page 243-253, March 2026.
ABSTRACT Previous studies on Cydia pomonella eggs have demonstrated reliable egg adhesion to the leaves and fruits of various apple cultivars. In contrast to biological substrates, this study is focused on standardised synthetic substrates to measure egg pull‐off forces and determine adhesive strength, allowing for an unbiased comparison with other ...
Loris Al Bitar, Claus Zebitz, Stanislav Gorb, Dagmar Voigt   +3 more
wiley   +1 more source

Dynamic left ventricular outflow tract obstruction in critical illness: etiology-driven management and the role of bedside transthoracic echocardiography. [PDF]

Crit Care
Li X, Lin Y, Wang W, Zou Y, Zhang Z, Wu F, Shang J, Song Y, Liang M, Zhou Q.   +9 more
europepmc   +1 more source

Processing and Characterization of Copper Reinforced Cyclic Olefin Copolymer Filaments for 3D Printing

Journal of Applied Polymer Science, Volume 143, Issue 5, February 5, 2026.
Graphical overview of the composite filament manufacturing steps. ABSTRACT This study presents the development and characterization of copper microparticle‐filled cyclic olefin copolymer (COC) composites as functional filaments for fused filament fabrication.
Elizabeta Forjan, Marijan‐Pere Marković, Katarina Šulek, Domagoj Vrsaljko   +3 more
wiley   +1 more source

Mechanical effects of taper angles in implant-abutment connection: a finite element study. [PDF]

Int J Implant Dent
Tokumoto M, Matsuzaki T, Sakai N, Atsuta I, Ayukawa Y.   +4 more
europepmc   +1 more source