Results 101 to 110 of about 241,214 (349)

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Dietary phytochemicals alleviate the premature skin aging: A comprehensive review

Experimental Gerontology
Skin aging, often called as premature skin aging, is the hastened deterioration of the skin resulting from multiple factors, including UV radiation, environmental contaminants, inadequate nutrition, stress, etc. Dietary phytochemicals, present in fruits,
Harpreet Singh, Y.T. Kamal, Jessica Pandohee, Arun Kumar Mishra, Aritra Biswas, Sourav Mohanto, Arvind Kumar, Sagnik Nag, Amrita Mishra, Mhaveer Singh, Himanshu Gupta, Hitesh Chopra   +11 more
doaj   +1 more source

Etiology and Management of Sexual Dysfunction [PDF]

, 2009
Sexual dysfunction is the impairment or disruption of any of the three phases of normal sexual functioning, including loss of libido, impairment of physiological arousal and loss, delay or alteration of orgasm.
Bevinahalli Nanjegowda, Raveesh, Muthugaduru Shivarudrappa, Narendra Kumar, Mysore Nagaraj, Anil Kumar, Pai, Nagesh Brahmavar, Rajagopal, Rajendra, Siddika, Nayeema   +5 more
core   +2 more sources

Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans [PDF]

, 2018
Sulfur Mustard (SM) is the most widely used chemical weapon. It was used in World War 1 and in the more recent Iran-Iraq conflict. Genetic toxicity and DNA alkylation effects of SM in molecular and animal experiments are well documented.
Ahmadimanesh, Mahnaz, BalaliMood, Mahdi, Behravan, Effat, Blain, Peter, Forghanifard, Mohammad Mahdi, Jowsey, Paul, Kalalinia, Fatemeh, Khateri, Shahriar, Moallem, Seyed Adel   +8 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Death Rate as a Demo-economic Factor of the Country's Labour Potential Reduction [PDF]

, 2016
The article deals with the impact of mortality rate on the reduction of labour potential. The authors determine the index of years of potential life lost, analyze the primary causes of deaths as well as provide some prognostic estimates concerning the ...
Kobelia, Z. (Zoryana), Ksyondz, S. (Sergey), Vodianka, L. (Liubov)   +2 more
core  

Schizophrenia in older adults [PDF]

, 2011
Although the number of persons over the age of 55 with schizophrenia is expected to double over the next 20 years, the research data on older people with schizophrenia is limited.
American Psychiatric Association, Bleuler, Bleuler, Bridge, Collier, Collier, Collier, Elizabeth Collier, Jeanne M. Sorrell, Palmer, Roth, Snowden, World Health Organization   +12 more
core   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The incidence of retinopathy of prematurity in different gestational ages [PDF]

, 2022
Amir Eftekhari Milani, Vahideh Manouchehri, Mohamad Reza Niyusha, Sadra Eftekhari Milani   +3 more
openalex   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source