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Connective tissue dysplasia as a predictor of premature skin aging
Background — One of the manifestations of connective tissue dysplasia (CTD) is premature skin aging. The latter can have different etiological factors.
Nikolai N. Potekaev +7 more
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Hutchinson-Gilford progeria syndrome and Werner syndrome are two of the best characterized human progeroid diseases with clinical features mimicking physiological aging at an early age. Both disorders have been the focus of intense research in recent years since they might provide insights into the pathology of normal human aging.
Fabio Coppedè +2 more
core +5 more sources
Our study aimed to develop a comprehensive approach to the management of patients with involutional skin changes, considering the predictors of premature skin aging.
Nikolai N. Potekaev +8 more
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PREMATURE AGING MARKERS IN WOMEN OF REPRODUCTIVE AGE WITH HYPOPITUITARISM
Background: Premature aging reduces quality of human life, leads to development of “old age diseases” in younger age, and also shortens life expectancy.
D. S. Mikhaylova, I. A. Ilovayskaya
doaj +3 more sources
Regional brain aging: premature aging of the domain general system predicts aphasia severity [PDF]
Premature brain aging is associated with poorer cognitive reserve and lower resilience to injury. When there are focal brain lesions, brain regions may age at different rates within the same individual.
Natalie Busby +12 more
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Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging—A Systematic Review
Skin, as the outermost organ of the body, is constantly exposed to both intrinsic and extrinsic causative factors of aging. Intrinsic aging is related to compromised cellular proliferative capacity, and may be accelerated by harmful environmental ...
Angelika Bielach-Bazyluk +6 more
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Premature aging in genetic diseases: what conclusions can be drawn for physiological aging [PDF]
According to current views the major hallmarks of physiological aging may be subdivided into three categories, primary causes of cellular damage (genomic instability, telomere attrition, loss of proteostasis, epigenetic alterations and compromised ...
Filip Milosic +2 more
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DNA-Related Pathways Defective in Human Premature Aging [PDF]
One of the major issues in studies on aging is the choice of biological model system. The human premature aging disorders represent excellent model systems for the study of the normal aging process, which occurs at a much earlier stage in life in these ...
Vilhelm A. Bohr
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The intersection of TREX1, cGAS, STING and the DNA damage theory of aging [PDF]
Genetic syndromes of immune dysregulation have opened a door toward understanding mechanisms linking inflammation, premature aging, and normal aging.
Kate M. Jones +8 more
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Dietary phytochemicals alleviate the premature skin aging: A comprehensive review
Skin aging, often called as premature skin aging, is the hastened deterioration of the skin resulting from multiple factors, including UV radiation, environmental contaminants, inadequate nutrition, stress, etc. Dietary phytochemicals, present in fruits,
Harpreet Singh +11 more
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