Results 11 to 20 of about 101,264 (202)

The epidemiology of premature aging and associated comorbidities [PDF]

open access: yesClinical Interventions in Aging, 2013
Fabio Coppedè Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy Abstract: Hutchinson–Gilford Progeria Syndrome and Werner syndrome, also known as childhood- and adulthood ...
Coppedè F
doaj   +2 more sources

High Cardiorespiratory Fitness Protects against Molecular Impairments of Metabolism, Heart, and Brain with Higher Efficacy in Obesity-Induced Premature Aging [PDF]

open access: yesEndocrinology and Metabolism, 2022
Background High cardiorespiratory fitness (CRF) protects against age-related diseases. However, the mechanisms mediating the protective effect of high intrinsic CRF against metabolic, cardiac, and brain impairments in non-obese versus obese conditions ...
Patcharapong Pantiya   +11 more
doaj   +1 more source

Healthy and premature aging of monocytes and macrophages

open access: yesFrontiers in Immunology
Aging is associated with immunosenescence, a decline in immune functions, but also with inflammaging, a chronic, low-grade inflammation, contributing to immunosenescence.
Syamantak Basu   +3 more
doaj   +2 more sources

Testicular aging, male fertility and beyond

open access: yesFrontiers in Endocrinology, 2022
Normal spermatogenesis and sperm function are crucial for male fertility. The effects of healthy testicular aging and testicular premature aging on spermatogenesis, sperm function, and the spermatogenesis microenvironment cannot be ignored. Compared with
Shijue Dong   +5 more
doaj   +1 more source

Early aging and premature vascular aging in chronic kidney disease [PDF]

open access: yes, 2023
Aging is the progressive decline of body functions and a number of chronic conditions can lead to premature aging characterized by frailty, a diseased vasculature, osteoporosis, and muscle wasting.
Peltek, Ibrahim Batuhan   +15 more
core   +1 more source

Impact of age, antiretroviral therapy, and cancer on epigenetic aging in people living with HIV

open access: yesCancer Medicine, 2023
Background Premature aging has been identified as a global risk factor for cancer. Causes of premature aging are multifactorial, including inflammation, infection, chronic stress, and lifestyle factors.
Yulan Qing   +7 more
doaj   +1 more source

Impact papers on aging in 2009 [PDF]

open access: yes, 2010
The editorial board of Aging reviews research papers published in 2009,which they believe have or will have a significant impact on aging research.Among many others, the topics include genes that accelerate aging or incontrast promote longevity in model ...
Sassone-Corsi, Paolo   +57 more
core   +1 more source

Specific premature epigenetic aging of cartilage in osteoarthritis [PDF]

open access: yes, 2016
Osteoarthritis (OA) is a disease affecting multiple tissues of the joints in the elderly, but most notably articular cartilage. Premature biological aging has been described in this tissue and in blood cells, suggesting a systemic component of premature ...
Rego Pérez, Ignacio   +23 more
core   +1 more source

Increased Brain Age Gap Estimate (BrainAGE) in Young Adults After Premature Birth

open access: yesFrontiers in Aging Neuroscience, 2021
Recent evidence suggests increased metabolic and physiologic aging rates in premature-born adults. While the lasting consequences of premature birth on human brain development are known, its impact on brain aging remains unclear.
Dennis M. Hedderich   +27 more
doaj   +1 more source

RETINOPATHY OF PREMATURITY AND MATERNAL AGE [PDF]

open access: yesRetina, 2010
To determine the risk factors, especially maternal risk factors, associated with the development of retinopathy of prematurity (ROP) in premature babies.A matched case-control study involving premature patients was undertaken retrospectively. The case group consisted of premature babies with the subsequent development of ROP.
Wei-Chi, Wu   +8 more
openaire   +2 more sources

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