Results 81 to 90 of about 241,214 (349)
Premature aging, allostasis and restorgenesis [PDF]
Spinal Cord, 2013 I feel that the highlight of my research activities is bringing the topic of ‘premature morbidity and aging’ (senectus praecox), in people with spinal cord injury (SCI) and other disabilities, into public awareness ...
openaire +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Are There Common Mechanisms Between the Hutchinson–Gilford Progeria Syndrome and Natural Aging?
Frontiers in Genetics, 2019 The Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging disease caused by mutations of the LMNA gene leading to increased production of a partially processed form of the nuclear fibrillar protein lamin A – progerin.
Vasily V. Ashapkin +3 more
doaj +1 more source
Clinical and laboratory criteria for occult form of premature ovarian failure [PDF]
Гинекология, 2018 Purpose of the study. To develop clinical and laboratory criteria characteristic of the occult (hidden) form of premature ovarian failure. Material and methods.
L A Marchenko, R I Mashaeva
doaj +1 more source
Social and medical aspects longevity [PDF]
, 2011 The article deals with the demographical problem's population aging, life expectancy, premature aging, are shown results on quality of life in countries in relation to different indexes, that form ...
Duque Kalderon, U. F. +3 more
core
High Preservation of CpG Cytosine Methylation Patterns at Imprinted Gene Loci in Liver and Brain of Aged Mice [PDF]
, 2013 A gradual loss of the correct patterning of 5-methyl cytosine marks in gene promoter regions has been implicated in aging and age-related diseases, most notably cancer.
Dollé, M.E.T. (Martijn) +6 more
core +1 more source
DNA damage induced during mitosis undergoes DNA repair synthesis. [PDF]
, 2020 Understanding the mitotic DNA damage response (DDR) is critical to our comprehension of cancer, premature aging and developmental disorders which are marked by DNA repair deficiencies.
Berns, Michael W +10 more
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV
Journal of Immunology Research, 2020 Chronic HIV-infected children suffer from premature aging and aging-related diseases. Viral replication induces an ongoing inflammation process, with the release of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns ...
Annalisa Dalzini +5 more
doaj +1 more source
Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy [PDF]
, 2016 Background: The uremic milieu exposes chronic kidney disease (CKD) patients to premature ageing processes. The impact of renal replacement therapy (dialysis and renal transplantation [RTx]) or immunosuppressive treatment regimens on ageing biomarkers has
Bárány, Peter +13 more
core +1 more source