Results 71 to 80 of about 886,795 (250)

Other title: [Kansas Department on Aging Overview]

open access: yes, 2009
application/pdf; "February 17, 2009."; Presentation before the Kansas Legislature, House Social Services Subcommittee on the Kansas Department on Aging, by Secretary Kathy Greenlee, Kansas Department on Aging.Presentation discussing the Governor's budget
Greenlee, Kathy.
core   +1 more source

Premature Aging Syndrome

open access: yes, 2016
Premature aging syndromes are human conditions in which multiple organs and tissues show features of accelerated aging. This chapter describes Hutchinson–Gilford Progeria Syndrome and Werner Syndrome, two of the best-characterized segmental progeroid ...
Fabio Coppedè   +2 more
core   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Other title: Kansas State Advisory Council on Aging report for fiscal years--Other title: Kansas Advisory Council on Aging annual report

open access: yes, 1979
The reports were prepared with the assistance of the Kansas Department on Aging.; Created in 1977 by the Kansas Act on the Aging, the ACA is represents different geographical, social and ethnic groups, with at least half its members being 60 years of age
Kansas Advisory Council on Aging.
core  

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan   +7 more
wiley   +1 more source

Trophoblast Extracellular Vesicles as Modulators of Keratinocyte Stress Response and Senescence

open access: yesLife
Keratinocyte stress, caused by various intrinsic and extrinsic factors, contributes to the overall aging process. D-galactose-induced metabolic/oxidative stress is a commonly used in vitro model for studying premature aging. Due to their rich composition
Mirjana Nacka-Aleksić   +6 more
doaj   +1 more source

Early podocyte injury and premature glomerular aging - Supplemental Material

open access: yes, 2023
Supplemental material for publication on early podocyte injury and premature glomerular aging.
Joseph C. Maggiore (17122728)   +13 more
core   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

Regional brain aging: premature aging of the domain general system predicts aphasia severity

open access: yesCommunications Biology
Premature brain aging is associated with poorer cognitive reserve and lower resilience to injury. When there are focal brain lesions, brain regions may age at different rates within the same individual.
Natalie Busby   +12 more
doaj   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic   +7 more
wiley   +1 more source

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