Results 141 to 150 of about 30,899 (323)

A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure

, 2009
BACKGROUND Three variants of the human INHA gene have been reported to be associated with premature ovarian failure (POF) in case-control studies involving a small number of patients and controls.
I. Giotti, A. Marozzi, R. Rossetti, T. Corre, J. Schuettler, S. Bione, Italian Network for the study of Ovarian Dysfunctions, P. Vogt, F. Torricelli, D. Toniolo, L. Persani   +10 more
core   +1 more source

POLG‐Related Parkinsonism with Good Response to Deep Brain Stimulation

Movement Disorders Clinical Practice, EarlyView.
Evdokia Efthymiou, Fabian Büchele, Sujitha Mahendran, Lennart Stieglitz, Bettina Balint   +4 more
wiley   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Reproductive outcomes in women with Hodgkin's lymphoma in a Danish fertility preservation cohort

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The risk of premature ovarian insufficiency increases with the intensity of alkylating chemotherapy. In general, fertility outcomes were favorable, but chances of live birth decreased with increased intensity of alkylating chemotherapy. Ovarian tissue transplantation enabled natural conception in women with premature ovarian insufficiency, supporting ...
Lotte Berdiin Colmorn, Elisabeth C. Larsen, Anette Tønnes Pedersen, Stine Gry Kristensen, Kirsten Tryde Macklon   +4 more
wiley   +1 more source

Assessment role of total phenols and flavonoids extracted from Pleurotus columbinus mushroom on the premature ovarian failure induced by chemotherapy in rats [PDF]

, 2021
Amal I. Hassan, Mona A. M. Ghoneim, Manal G. Mahmoud, Mohsen S. Asker   +3 more
openalex   +1 more source

Genes involved in human premature ovarian failure

, 2010
Premature ovarian failure (POF) is an ovarian defect characterized by the premature depletion of ovarian follicles before the age of 40 years, representing one major cause of female infertility.
R. Rossetti, Raffaella Rossetti, C. Cacciatore, Chiara Cacciatore, Luca Persani, L. Persani   +5 more
core   +1 more source

Management of congenital female genital tract anomalies related to primary amenorrhea and/or cyclic abdominal pain: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Overall, 21 patients with uterine, cervical, and vaginal aplasia were treated successfully with neovagina formation. In 6 out of 8 patients, with obstructed uterine cavity, anastomosis was successful; one underwent hysterectomy and one elective hemi‐hysterectomy.
Grigoris F. Grimbizis, Sofia Tsiapakidou, Eirini Iordanidou, Georgios Kioussis, Anastasia Vatopoulou, Theodoros Theodoridis   +5 more
wiley   +1 more source

Technologized Reproduction in Space: A Space‐Bioethical Case for Assisted Procreation

Bioethics, EarlyView.
ABSTRACT With the increasing feasibility of space colonization, the issue of reproduction in space is becoming more relevant. As new settlements on the Moon, Mars, and other celestial bodies emerge, ensuring generational continuity will be essential for the survival and growth of these communities.
Maurizio Balistreri, Konrad Szocik
wiley   +1 more source

Mesenchymal stem cells and their promise in reversing ovarian aging

Journal of Ovarian Research
Ovarian aging is accompanied by a decline in the quantity and quality of follicles, leading to reduced fertility. Ovarian aging encompasses natural aging due to DNA damage, telomere attrition, and mitochondrial dysfunction, as well as a pathological ...
Dongmei Yao, Hong Chen, Jianlong Yuan, Peixin Xu, Xin Guo, Jing Gao, Xin Li, Tong Wang, Yurong Wang, Bingchun Liu, Yang Liu   +10 more
doaj   +1 more source

Targeting Cell Cycle Vulnerabilities in Cancers: Emerging Strategies for Therapeutic Development

Cancer Science, EarlyView.
Dysregulated cell cycle control often involves alternative compensatory pathways in cancers to maintain its robustness but provide unique targetable vulnerabilities. We overview recent insights on cancer‐specific vulnerabilities across the cell cycle and discuss how these can be used to develop new therapeutic strategies.
Nana Kamakura, Minji Jo, Motoko Takahashi, Toru Hirota   +3 more
wiley   +1 more source