Results 161 to 170 of about 2,087,459 (277)

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Early‐ vs. late‐onset gestational diabetes: Differential impact on maternal and neonatal outcomes

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 2012-2022, October 2026.
Early‐onset gestational diabetes mellitus (diagnosed before 20 weeks) identifies a clinically higher‐risk phenotype than late‐onset GDM (24–28 weeks), with greater insulin requirement and higher adjusted risks of preeclampsia, cesarean delivery, preterm birth, and adverse neonatal outcomes.
Baolai Li, Wenjun Ji, Rui Zhao, Jinchun Zhang   +3 more
wiley   +1 more source

Zuogui Wan alleviated radiation-induced premature ovarian failure and ferroptosis via miR-21-5p/DNMT3b. [PDF]

J Ovarian Res
Liu Y, Chen M, Li M, Li Z, Huang H.
europepmc   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, Volume 13, Issue 51, 14 September 2026.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

The characterization of patients with premature ovarian failure, endometriosis, and polycystic ovary syndrome in women attending comprehensive health centers in Urmia, Iran. [PDF]

BMC Womens Health
Fathi B, Ghasemnejad-Berenji H, Hashemi SS, Sadeghpour S, Hosseini A, Alinejad V, Firooziyan S, Manafpour M, Bagheri M.   +8 more
europepmc   +1 more source

Mechanism of platelet-rich plasma in improving cyclophosphamide-induced premature ovarian failure in rats. [PDF]

Stem Cell Res Ther
Zhao T, Xiao X, Li L, Wei Y, Shi H, Yang G, Yuan T.   +6 more
europepmc   +1 more source

TSG From Polygonum multiflorum Thunb. Attenuates Experimental Premature Ovarian Insufficiency in Association With Reduced ZBP1/PANoptosis Signaling

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This study shows that TSG, the major bioactive constituent of Polygonum multiflorum Thunb., ameliorates POI in association with suppression of ZBP1‐driven PANoptosis. In a POI rat model, TSG restored estrous cyclicity, improved hormone profiles, and preserved follicular reserve.
Jinhong Li, Tiao Xie, Chang Lin, Danhong Peng, Qin Shi, Can Zhu   +5 more
wiley   +1 more source

Hydroxychloroquine alleviates cyclophosphamide-induced premature ovarian failure by attenuating granulosa cell senescence and modulating the mtDNA-cGAS pathway. [PDF]

NPJ Aging
Su D, Ma R, Su H, Tan C, Zhu Y, Liu Y, Jiang X, Sun X, Lei T, Zhang M, Lin S, Qi Y, Yang X.   +12 more
europepmc   +1 more source

Bushen Huatan Formula Ameliorates Early Chronic Low‐Grade Inflammation in Obese PCOS Via the TLR4/NF‐κB Signaling Pathway: An Integrated Network Pharmacology and Experimental Study

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Objective This study used an integrated network pharmacology and experimental strategy to investigate how Bushen Huatan Formula (BHF) mitigates early‐stage chronic low‐grade inflammation in obese polycystic ovary syndrome (PCOS). Methods Candidate components and targets of BHF were retrieved from the TCMSP database, and protein–protein ...
Jianing Zhang, Fangyun Gu, Yunyun Li, Xiaoling Feng, Hongying Kuang, Fang Xu, Miao Sun   +6 more
wiley   +1 more source

Establishment of an optimized chemotherapy-induced mouse model for premature ovarian failure: protocol and findings. [PDF]

Aging (Albany NY)
Yavari N, Zaeemzadeh N, Gharesi-Fard B, Ardehjani NA, Rastegar T, Amidi F.   +5 more
europepmc   +1 more source