Results 181 to 190 of about 2,087,459 (277)

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

Comprehensive profiling of cell‐free RNA in seminal plasma reveals functional links to spermatogenic impairment

open access: yes
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Qing Zhou   +15 more
wiley   +1 more source

Amino Acid Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su   +7 more
wiley   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao   +10 more
wiley   +1 more source

Reproductive Changes in Women with Premature Ovarian Failure

open access: yes
Failure to become pregnant after therapy forces the patient to use assisted reproductive technologies using donor embryos and oocytes, while the effectiveness of in vitro fertilization does not exceed 58%.
Mo‘minjonovna, B. M. (Boboxonova)
core  

High‐Content CRISPR Screening: Methods and Applications

open access: yesMedComm, Volume 7, Issue 9, September 2026.
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang   +6 more
wiley   +1 more source

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