hnRNPA2B1 restrains granulosa cell ferroptosis by m<sup>6</sup>A/SLC7A11 in premature ovarian failure. [PDF]
Xiong J, He L, Zhang Y, Zhao X.
europepmc +1 more source
Mitochondrial Haplotype Shapes the Trajectory of Ovarian Aging in Genetically Heterogeneous Rats
Using genetically heterogeneous rats carrying divergent mitochondrial haplotypes on a randomized nuclear background, we show that mtDNA variation modifies the rate of ovarian aging. OKC‐HETW ovaries showed bioenergetic deficits, reduced mtDNA copy number, and impaired TFAM–mtDNA binding by 4 months of age, with early fibrosis and immune infiltration ...
Subhasri Biswas +11 more
wiley +1 more source
The effects of probiotics, prebiotics, and synbiotics on aversive memory in a premature ovarian failure model in rat. [PDF]
Madahali MH +4 more
europepmc +1 more source
Overall, 21 patients with uterine, cervical, and vaginal aplasia were treated successfully with neovagina formation. In 6 out of 8 patients, with obstructed uterine cavity, anastomosis was successful; one underwent hysterectomy and one elective hemi‐hysterectomy.
Grigoris F. Grimbizis +5 more
wiley +1 more source
Yangjing Shugan decoction targets the Sirt1/Nrf2 antioxidant pathway and gut microbiota-metabolite axis to protect against premature ovarian failure. [PDF]
Yang L +9 more
europepmc +1 more source
Abstract Objective Premature ovarian insufficiency (POI) and early menopause (EM) can have life‐altering physical and psychological impacts, with potential consequences for an individual's sense of self. However, understanding of these potential consequences is limited, with much of the literature generalizing such experiences from naturally occurring ...
Lisa M. Seberry +3 more
wiley +1 more source
Optimal transplantation strategies for stem cell treatment in premature ovarian failure: a network meta-analysis. [PDF]
Ziwei G, Shuang N, Di W, Li J.
europepmc +1 more source
Targeting Cell Cycle Vulnerabilities in Cancers: Emerging Strategies for Therapeutic Development
Dysregulated cell cycle control often involves alternative compensatory pathways in cancers to maintain its robustness but provide unique targetable vulnerabilities. We overview recent insights on cancer‐specific vulnerabilities across the cell cycle and discuss how these can be used to develop new therapeutic strategies.
Nana Kamakura +3 more
wiley +1 more source
Correlation between intestinal flora and glucuronidase indexes and sex hormone levels and their diagnostic efficacy evaluation for premature ovarian failure. [PDF]
Zhang Y +6 more
europepmc +1 more source

