Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu +5 more
wiley +1 more source
Uncovering the Mechanism of Quercetin in the Treatment of Premature Ovarian Failure: A Multi-Faceted Approach Integrating Network Pharmacology, Bioinformatics Analysis and Experimental Validation. [PDF]
Zhefen M +5 more
europepmc +1 more source
Abstract For over four decades we have collaborated as a team of anthropologists and Indigenous Elders of the Yanyuwa language group. The Yanyuwa are the Indigenous owners of lands and waters in Australia's Gulf of Carpentaria. While medicalized healthcare has not been our specific research focus, wellness and ill health have been recurring themes ...
Amanda Kearney +3 more
wiley +1 more source
An Investigation of the Effects of Melatonin and Vitamin D on the Ovaries of a Rat Model of Premature Ovarian Failure Induced by Cyclophosphamide. [PDF]
Karaoğlan Ö +4 more
europepmc +1 more source
The incredible vulnerability that reproduction poses for plant species in a warming world
Generalized plant responses to heat stress across whole‐plant and reproductive scales. Summary Temperatures are rising globally and threatening the persistence of natural plant populations. Elevated temperatures disrupt gametogenesis, fertilization, and seed filling, often at lower thresholds than those affecting photosynthesis, growth, or survival ...
Derek A. Denney +4 more
wiley +1 more source
Notch2 improves granulosa cell functions in premature ovarian failure by activating the Wnt2/β-catenin pathway. [PDF]
Liang X, Li N, Wu S.
europepmc +1 more source
ABSTRACT Bovine embryo transfer (ET) has been a consistently growing market worldwide with in vitro produced (IVP) embryos now far outnumbering those produced by traditional superovulation. Because transfer of a viable blastocyst‐stage embryo to the uterus bypasses many of the potential biological causes of early pregnancy failure associated with ...
Ana Clara Canto Souza, Pat Lonergan
wiley +1 more source
Carvacrol ameliorates cyclophosphamide-induced rat premature ovarian failure and uterine fibrosis via regulating PI3K/AKT/FOXO3a signaling pathway. [PDF]
El-Gendy ZA +3 more
europepmc +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source

