Results 171 to 180 of about 13,204 (244)

Beyond the Known and Established Neurodegenerative Effects: Roles of APOE Across a Wide Spectrum of Pathophysiological Condition

open access: yesMedComm, Volume 7, Issue 6, June 2026.
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina   +5 more
wiley   +1 more source

Large-scale analysis of FMR1 CGG repeat length and risk of premature ovarian insufficiency in over 92 000 women. [PDF]

open access: yesHum Reprod
Morbey EJ   +7 more
europepmc   +1 more source

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang   +12 more
wiley   +1 more source

Clinical Features and PLCZ1 Gene Variants in Two Cases of Male Infertility: A Case Series and Literature Review

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
Our study expands the variant spectrum of PLCZ1, enriches the clinical characteristics of PLCZ1, and provides a solid base for the genetic counseling, diagnosis, and treatment of this condition. ABSTRACT Background Variations in the PLCZ1 gene can lead to male infertility (MIM #617214), an autosomal recessive disorder characterized by failure or ...
Jinwei Yang   +12 more
wiley   +1 more source

Early Menopause/Premature Ovarian Insufficiency

open access: yesSeminars in Reproductive Medicine, 2020
Vincent, Amanda J., Laven, Joop S.
openaire   +1 more source

Fertility Awareness and Attitudes Toward Parenthood Among University Students in Chitwan, Nepal: A Cross‐Sectional Study

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
University students show limited fertility awareness and less favorable attitudes toward parenthood. Misconceptions about age‐related fertility decline and infertility risks may delay informed decisions. Attitudes vary by age, ethnicity, and religion, highlighting the need for structured, age‐appropriate fertility education and counseling to support ...
Osin Gurung   +3 more
wiley   +1 more source

AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén   +44 more
wiley   +1 more source

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